Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing.

Creator(s)

Tamorah R. Lewis, Children's Mercy HospitalFollow
Leon Van Haandel, Children's Mercy Hospital
Allison Scott, Children's Mercy HospitalFollow
J Steven Leeder, Children's Mercy HospitalFollow

Document Type

Response or Comment

Publication Date

9-2018

Identifier

DOI: 10.1038/s41390-018-0051-7; PMCID: PMC6258260

Journal Title

Pediatric research

Volume

84

Issue

3

First Page

325

Last Page

327

MeSH Keywords

Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Glucuronides; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Male; Urine Specimen Collection

Keywords

Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Glucuronides; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Male; Urine Specimen Collection

Comments

Grant support

• P50 HD090258/HD/NICHD NIH HHS/United States
• U54 HD090258/HD/NICHD NIH HHS/United States

Recommended Citation

Lewis T, Van Haandel L, Scott A, Leeder JS. Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing. Pediatr Res. 2018;84(3):325-327. doi:10.1038/s41390-018-0051-7