Safety issues related to intravenous contrast agent use in magnetic resonance imaging.
Document Type
Article
Publication Date
5-2021
Identifier
DOI: 10.1007/s00247-020-04896-7
Abstract
Gadolinium-based contrast agents (GBCAs) have been used to improve image quality of MRI examinations for decades and have an excellent overall safety record. However, there are well-documented risks associated with GBCAs and our understanding and management of these risks continue to evolve. The purpose of this review is to discuss the safety of GBCAs used in MRI in adult and pediatric populations. We focus particular attention on acute adverse reactions, nephrogenic systemic fibrosis and gadolinium deposition. We also discuss the non-GBCA MRI contrast agent ferumoxytol, which is increasing in use and has its own risk profile. Finally, we identify special populations at higher risk of harm from GBCA administration.
Journal Title
Pediatric radiology
Volume
51
Issue
5
First Page
736
Last Page
747
Keywords
Adverse reaction; Children; Gadolinium deposition; Gadolinium-based contrast agent; Magnetic resonance imaging; Nephrogenic systemic fibrosis; Safety
Recommended Citation
Ponrartana S, Moore MM, Chan SS, Victoria T, Dillman JR, Chavhan GB. Safety issues related to intravenous contrast agent use in magnetic resonance imaging. Pediatr Radiol. 2021;51(5):736-747. doi:10.1007/s00247-020-04896-7
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