Effects of an acute bout of resistance exercise on fiber-type specific to GLUT4 and IGF-1R expression.

Creator(s)

Philip M. Gallagher
Chad D. Touchberry
Kelli M. Teson, Children's Mercy HospitalFollow
Everlee McCabe
Michelle Tehel
Michael J. Wacker

Document Type

Article

Publication Date

5-2013

Identifier

DOI: 10.1139/apnm-2012-0301

Abstract

The effects of resistance exercise on fiber-type-specific expression of insulin-like growth factor I receptor (IGF-1R) and glucose transporter 4 (GLUT4) was determined in 6 healthy males. The expression of both genes increased in Type I fibers (p < 0.05), but only GLUT4 increased (p < 0.05) in Type II fibers. These data demonstrates that an acute bout of resistance exercise can up-regulate mechanisms of glucose uptake in slow and fast-twitch fibers, but the IGF signaling axis may not be as effective in fast-twitch fibers.

Journal Title

Appl Physiol Nutr Metab

Volume

38

Issue

5

First Page

581

Last Page

586

MeSH Keywords

Dietary Fiber; Exercise; Glucose Transporter Type 4; Humans; Insulin-Like Growth Factor I; Muscle Fibers, Fast-Twitch; Signal Transduction

Keywords

Dietary Fiber; Exercise; Glucose Transporter Type 4; Insulin-Like Growth Factor I; Muscle Fibers, Fast-Twitch; Signal Transduction

Recommended Citation

Gallagher, P. M., Touchberry, C. D., Teson, K. M., McCabe, E., Tehel, M., Wacker, M. J. Effects of an acute bout of resistance exercise on fiber-type specific to GLUT4 and IGF-1R expression. Appl Physiol Nutr Metab 38, 581-586 (2013).