Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values.
Document Type
Article
Publication Date
1-1-2021
Identifier
DOI: 10.3928/01913913-20200910-03
Abstract
PURPOSE: To provide normative data of full-field electro-retinogram (ERG) responses in the pediatric population using the RETeval ERG device (LKC Technologies, Inc) in healthy children without evidence of retinal disease.
METHODS: This was a single-site cross-sectional study of healthy pediatric patients with normal dilated fundus examinations and no known retinal diseases. Participants were recruited to undergo dilated full-field ERG using the handheld RETeval device. The International Society for Clinical Electrophysiology of Vision 5-step protocol was used. Photopic and dark-adapted scotopic responses were recorded using skin electrodes.
RESULTS: Main outcome measures were normative RETeval ERG values and correlation of age with measured ERG parameters. Thirty-eight eyes of 20 healthy patients (aged 4 to 17 years) were included in the study. Of the 20 normal patients, 9 were male and 11 were female. Normative mean, median, and range values were recorded for the measured full-field ERG parameters. Pearson correlation was moderately positive between age and oscillatory potential and scotopic dim flash amplitude (r = 0.59, P = .006 for both). A positive correlation was also found between age and cone a-wave implicit time (r = 0.67, P = .001).
CONCLUSIONS: The handheld RETeval system is a useful tool for obtaining full-field ERGs in children without anesthesia. Moderate positive correlations were observed between age and oscillatory potential and scotopic dim flash amplitude. A strong correlation was found between age and cone a-wave implicit time. The current study provides a baseline of normative full-field ERG values in children. [J Pediatr Ophthalmol Strabismus. 2021;58(1):17-22.].
Journal Title
Journal of pediatric ophthalmology and strabismus
Volume
58
Issue
1
First Page
17
Last Page
22
Recommended Citation
Soekamto CD, Gupta R, Keck KM. Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values. J Pediatr Ophthalmol Strabismus. 2021;58(1):17-22. doi:10.3928/01913913-20200910-03