Document Type
Article
Publication Date
10-20-2021
Identifier
DOI: 10.1177/2329048X211048065; PMCID: PMC8532233
Abstract
Diffuse Lipomatosis is a dermatological lesion consisting of a poorly circumscribed, infiltrative overgrowth of mature adipose tissue that usually affects the trunk and the extremities. The lesions in the Tuberous Sclerosis Complex (TSC) are usually hamartomatous in nature, but lesions arising from adipocytes are rare. There are only three previous reports of association of TSC with diffuse lipomatosis. Herein we present a case series of diffuse lipomatosis in three subjects with TSC and proceed to review the literature for any other reported cases. On the basis of the three index cases and identification of three more cases in the literature, we believe that there is an association of diffuse lipomatosis with TSC that has not been appreciated until now. We believe that this association in some selected cases will serve to improve diagnosis, surveillance, and management..
Journal Title
Child Neurol Open
Volume
8
First Page
2329048
Last Page
2329048
Keywords
dermatological lesion; diffuse lipomatosis; lipoma; tuberous sclerosis; tuberous sclerosis complex; tuberous sclerosis surveillance
Recommended Citation
Ilyas M, Quezada J, Opfer EK. Lipomatous Infiltration in Tuberous Sclerosis Complex - A Case Series and Literature Review. Child Neurol Open. 2021;8:2329048X211048065. Published 2021 Oct 20. doi:10.1177/2329048X211048065
Comments
This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Publisher's Link: https://doi.org/10.1177%2F2329048X211048065