The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

Creator(s)

Andrea Gaedigk, Children's Mercy Kansas CityFollow
Magnus Ingelman-Sundberg, Karolinska InstituteFollow
Neil A. Miller, Children's Mercy Kansas CityFollow
J Steven Leeder, Children's Mercy Kansas CityFollow
Michelle Whirl-Carrillo, Stanford UniversityFollow
Teri E. Klein, Stanford UniversityFollow

Document Type

Article

Publication Date

3-2018

Identifier

29134625

Abstract

The Human Cytochrome P450 (CYP) Allele Nomenclature Database, a critical resource to the pharmacogenetics and genomics communities, will be transitioning to the Pharmacogene Variation (PharmVar) Consortium. In this report we provide a summary of the current database, provide an overview of the PharmVar consortium and highlight the PharmVar database which will serve as the new home for pharmacogene nomenclature.

Journal Title

Clin Pharmacol Ther

Volume

103

Issue

3

First Page

399

Last Page

401

MeSH Keywords

Cytochrome P-450 Enzyme System; Alleles/terminology

Keywords

Cytochrome P450; star nomenclature; allele designation; PharmGKB; CPIC

Comments

Grant support

• R24 GM061374/GM/NIGMS NIH HHS/United States
• R24 GM123930/GM/NIGMS NIH HHS/United States

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Publisher's Link: https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.910

Recommended Citation

Gaedigk A, Ingelman-Sundberg M, Miller NA, et al. The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database. Clin Pharmacol Ther. 2018;103(3):399-401. doi:10.1002/cpt.910