Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children.

Creator(s)

Dithi Banerjee, Children's Mercy HospitalFollow
Anjana Sasidharan, Children's Mercy HospitalFollow
Ayah Abdulhamid, Children's Mercy HospitalFollow
Esmeralda M. Orosco, Children's Mercy HospitalFollow
Jennifer Watts, Children's Mercy HospitalFollow
Jennifer E. Schuster, Children's Mercy HospitalFollow
Angela Myers, Children's Mercy HospitalFollow
Gina Weddle, Children's Mercy HospitalFollow
Rangaraj Selvarangan, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

11-11-2021

Identifier

DOI: 10.1093/jpids/piab058; PMCID: PMC8344893

Abstract

Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.

Journal Title

J Pediatric Infect Dis Soc

Volume

10

Issue

10

First Page

967

Last Page

969

MeSH Keywords

COVID-19; Child; Humans; Molecular Diagnostic Techniques; Nasopharynx; SARS-CoV-2; Saliva; Specimen Handling

Keywords

SARS-CoV-2; molecular assay; pediatric; saliva

Recommended Citation

Banerjee D, Sasidharan A, Abdulhamid A, et al. Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children. J Pediatric Infect Dis Soc. 2021;10(10):967-969. doi:10.1093/jpids/piab058