Document Type
Article
Publication Date
1-13-2023
Identifier
DOI: 10.3390/nu15020419; PMCID: PMC9863135
Abstract
(1) Background: Sleep, a physiological necessity, has strong inflammatory underpinnings. Diet is a strong moderator of systemic inflammation. This study explored the associations between the Dietary Inflammatory Index (DII®) and sleep duration, timing, and quality from the Energy Balance Study (EBS). (2) Methods: The EBS (n = 427) prospectively explored energy intake, expenditure, and body composition. Sleep was measured using BodyMedia's SenseWear® armband. DII scores were calculated from three unannounced dietary recalls (baseline, 1-, 2-, and 3-years). The DII was analyzed continuously and categorically (very anti-, moderately anti-, neutral, and pro-inflammatory). Linear mixed-effects models estimated the DII score impact on sleep parameters. (3) Results: Compared with the very anti-inflammatory category, the pro-inflammatory category was more likely to be female (58% vs. 39%, p = 0.02) and African American (27% vs. 3%, p < 0.01). For every one-unit increase in the change in DII score (i.e., diets became more pro-inflammatory), wake-after-sleep-onset (WASO) increased (βChange = 1.00, p = 0.01), sleep efficiency decreased (βChange = -0.16, p < 0.05), and bedtime (βChange = 1.86, p = 0.04) and waketime became later (βChange = 1.90, p < 0.05). Associations between bedtime and the DII were stronger among African Americans (βChange = 6.05, p < 0.01) than European Americans (βChange = 0.52, p = 0.64). (4) Conclusions: Future studies should address worsening sleep quality from inflammatory diets, leading to negative health outcomes, and explore potential demographic differences.
Journal Title
Nutrients
Volume
15
Issue
2
MeSH Keywords
Humans; Female; Male; Diet; Inflammation; Sleep; Energy Intake; Polysomnography
Keywords
Dietary Inflammatory Index (DII); bedtime; diet quality; inflammation; wake-after-sleep-onset; waketime
Recommended Citation
Farrell ET, Wirth MD, McLain AC, et al. Associations between the Dietary Inflammatory Index and Sleep Metrics in the Energy Balance Study (EBS). Nutrients. 2023;15(2):419. Published 2023 Jan 13. doi:10.3390/nu15020419
Comments
Grant support
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Publisher's Link: https://www.mdpi.com/2072-6643/15/2/419