New insights into the treatment of acute otitis media.

Creator(s)

Rana El Feghaly, Children's Mercy Kansas CityFollow
Amanda Nedved, Children's Mercy HospitalFollow
Sophie E. Katz
Holly M. Frost

Document Type

Article

Publication Date

5-2023

Identifier

DOI: 10.1080/14787210.2023.2206565

Abstract

INTRODUCTION: Acute otitis media (AOM) affects most (80%) children by 5 years of age and is the most common reason children are prescribed antibiotics. The epidemiology of AOM has changed considerably since the widespread use of pneumococcal conjugate vaccines, which has broad-reaching implications for management.

AREAS COVERED: In this narrative review, we cover the epidemiology of AOM, best practices for diagnosis and management, new diagnostic technology, effective stewardship interventions, and future directions of the field. Literature review was performed using PubMed and ClinicalTrials.gov.

EXPERT OPINION: Inaccurate diagnoses, unnecessary antibiotic use, and increasing antimicrobial resistance remain major challenges in AOM management. Fortunately, effective tools and interventions to improve diagnostic accuracy, de-implement unnecessary antibiotic use, and individualize care are on the horizon. Successful scaling of these tools and interventions will be critical to improving overall care for children.

Journal Title

Expert review of anti-infective therapy

Volume

21

Issue

5

First Page

523

Last Page

534

MeSH Keywords

Child; Humans; Infant; Acute Disease; Otitis Media; Anti-Bacterial Agents; Pneumococcal Vaccines

Keywords

Acute otitis media; amoxicillin; antibiotic stewardship; pneumococcal vaccines; treatment

Comments

Grant support

• K23 HD099925/HD/NICHD NIH HHS/United States

Recommended Citation

El Feghaly RE, Nedved A, Katz SE, Frost HM. New insights into the treatment of acute otitis media. Expert Rev Anti Infect Ther. 2023;21(5):523-534. doi:10.1080/14787210.2023.2206565