Document Type

Article

Publication Date

7-17-2023

Identifier

DOI: 10.3171/CASE23252

Abstract

BACKGROUND: While hypoglycorrhachia is observed and managed frequently, there are few reports in the literature of clinically significant hyperglycorrhachia after neurosurgery. Understanding the effects and management of severe hyperglycorrhachia is important to the neurosurgeon and neurocritical care teams who care for patients in these rare scenarios.

OBSERVATIONS: The authors present the case of a 3-month-old male with congenital hydrocephalus who faced profound hyperglycorrhachia and status epilepticus after an endoscopic aqueductoplasty using an irrigant composed of lactated Ringer's solution with dextrose 5% in water. A multidisciplinary approach was developed to monitor and treat the patient's seizures and cerebrospinal fluid (CSF) osmolytes.

LESSONS: This case provides several learning opportunities for understanding CSF physiology, pathogenesis of common brain injuries related to osmotic shifts and inflammatory states, as well as clinical management of hyperglycorrhachia. It also reiterates the significance of meticulous intraoperative assessment to avoid preventable medical errors.

Journal Title

J Neurosurg Case Lessons

Volume

6

Issue

3

Keywords

endoscopy; hyperglycorrhachia; neurocritical care; seizure

Comments

CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Publisher's Link: https://doi.org/10.3171/case23252

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