Transpyloric feeding is associated with adverse in-hospital outcomes in infants with severe bronchopulmonary dysplasia.

Document Type

Article

Publication Date

2-2024

Identifier

DOI: 10.1038/s41372-024-01867-w

Abstract

OBJECTIVE: To estimate the association of transpyloric feeding (TPF) with the composite outcome of tracheostomy or death for patients with severe bronchopulmonary dysplasia (sBPD).

STUDY DESIGN: Retrospective multi-center cohort study of preterm infants36, 44, or 50 weeks post-menstrual age to those who did not receive TPF at any of those timepoints. Odds ratios were adjusted for gestational age, small for gestational age, male sex, and invasive ventilation and FiO2 at 36 weeks.

RESULTS: Among 1039 patients, 129 (12%) received TPF. TPF was associated with an increased odds of tracheostomy or death (aOR 3.5, 95% CI 2.0-6.1) and prolonged length of stay or death (aOR 3.1, 95% CI 1.9-5.2).

CONCLUSIONS: Use of TPF in sBPD after 36 weeks was infrequent and associated with worse in-hospital outcomes, even after adjusting for respiratory severity at 36 weeks.

Journal Title

Journal of perinatology : official journal of the California Perinatal Association

Volume

44

Issue

2

First Page

307

Last Page

313

MeSH Keywords

Female; Humans; Infant, Newborn; Male; Bronchopulmonary Dysplasia; Cohort Studies; Gestational Age; Infant, Premature; Intensive Care Units, Neonatal; Retrospective Studies

Keywords

Bronchopulmonary Dysplasia; Cohort Studies; Gestational Age; Neonatal Intensive Care Units; Retrospective Studies

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