Clinical Consensus Statement on the Use of Indocyanine Green Fluorescence-guided Surgery in Pediatric Patients.
Document Type
Article
Publication Date
11-2024
Identifier
DOI: 10.1016/j.jpedsurg.2024.07.042
Abstract
BACKGROUND AND AIMS: Indocyanine Green Fluorescence (ICG-F)- guided surgery is becoming an increasingly helpful tool in pediatric surgical care. This consensus statement investigates the utility of ICG-F in various pediatric surgical applications, primarily focusing on its evidence base, safety, indications, use across different surgical specialties and dosing strategies. The aim is to establish an international consensus for ICG-F use in pediatric surgery.
METHODS: An international panel of 15 pediatric surgeons from 9 countries was assembled. The structured process consisted of a rapid scoping review, iterative discussion sessions, mixed-methods studies with key stakeholders, and voting rounds on individual statements to create draft consensus statements.
RESULTS: 100 articles were identified during the review and summarized by application. Based on this condensed evidence, consensus statements were generated after 3 iterative rounds of anonymous voting. Key areas of agreement were quality of evidence, the safety of ICG, pediatric surgical indications, utilization per surgical specialty, and dosing of ICG.
CONCLUSION: This consensus statement aims to guide healthcare professionals in managing ICG-F use in pediatric surgical cases based on the best available evidence, key stakeholder consultation, and expert opinions. Despite ICG-F's promising potential, the need for higher-quality evidence, prospective trials, and safety studies is underscored. The consensus also provides a framework for pediatric surgeons to utilize ICG-F effectively.
LEVEL OF EVIDENCE: III.
Journal Title
Journal of pediatric surgery
Volume
59
Issue
11
First Page
161657
Last Page
161657
MeSH Keywords
Indocyanine Green; Humans; Child; Surgery, Computer-Assisted; Consensus; Pediatrics; Coloring Agents; Fluorescence
Keywords
Fluorescein sodium; Fluorescence angiography; Fluorescence imaging; Fluorescence-guided surgery; Iindocyanine green laser angiography; Immuno-fluorescence; Indocyanine green; Indocyanine green fluorescence; Near-infrared dyes; Pediatric surgery; Tissue perfusion
Recommended Citation
Szavay PO, Bondoc A, Esposito C, et al. Clinical Consensus Statement on the Use of Indocyanine Green Fluorescence-guided Surgery in Pediatric Patients. J Pediatr Surg. 2024;59(11):161657. doi:10.1016/j.jpedsurg.2024.07.042
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