The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation.
Document Type
Article
Publication Date
1-1-2025
Identifier
DOI: 10.1097/FPC.0000000000000547
Abstract
Pharmacogenetics promises to optimize treatment-related outcomes by informing optimal drug selection and dosing based on an individual's genotype in conjunction with other important clinical factors. Despite significant evidence of genetic associations with drug response, pharmacogenetic testing has not been widely implemented into clinical practice. Among the barriers to broad implementation are limited guidance for how to successfully integrate testing into clinical workflows and limited data on outcomes with pharmacogenetic implementation in clinical practice. The Pharmacogenomics Global Research Network Implementation Working Group seeks to engage institutions globally that have implemented pharmacogenetic testing into clinical practice or are in the process or planning stages of implementing testing to collectively disseminate data on implementation strategies, metrics, and health-related outcomes with the use of genotype-guided drug therapy to ultimately help advance pharmacogenetic implementation. This paper describes the goals, structure, and initial projects of the group in addition to implementation priorities across sites and future collaborative opportunities.
Journal Title
Pharmacogenet Genomics
Volume
35
Issue
1
First Page
1
Last Page
11
MeSH Keywords
Humans; Pharmacogenetics; Pharmacogenomic Testing; Precision Medicine
Keywords
Pharmacogenetics; Pharmacogenomic Testing; Precision Medicine
Recommended Citation
Cavallari LH, Hicks JK, Patel JN, et al. The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation. Pharmacogenet Genomics. 2025;35(1):1-11. doi:10.1097/FPC.0000000000000547
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