Primary ovarian insufficiency and Turner syndrome
Document Type
Book Chapter
Publication Date
2025
Identifier
DOI: /10.1016/B978-0-443-10512-8.00027-8
Abstract
Primary Ovarian Insufficiency (POI) is characterized by oligomenorrhea/amenorrhea lasting 4 or more months, along with elevated FSH levels exceeding 25 IU/L on two occasions, one month apart, prior to age 40. POI manifests in various ways, including delayed puberty, primary or secondary amenorrhea, oligomenorrhea, infertility, vasomotor symptoms, vaginal dryness, or mood changes. The initial assessment for POI involves a comprehensive examination encompassing beta-HCG, prolactin, thyroid function studies, FSH, LH, estradiol, AMH, chromosome analysis, fragile X testing, 21-hydroxylase antibodies, thyroid peroxidase antibodies. In Turner syndrome, is it crucial to evaluate for potential comorbidities by conducting appropriate screening, and making relevant referrals. Hormone replacement therapy is recommended or individuals with POI.
Journal Title
NASPAG Essentials of Pediatric & Adolescent Gynecology
First Page
183
Last Page
189
Recommended Citation
Kastury RD, Dowlut-McElroy T. Primary ovarian insufficiency and Turner syndrome. NASPAG Essentials of Pediatric & Adolescent Gynecology. Published online 2025:183-189. doi:10.1016/b978-0-443-10512-8.00027-8
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