Document Type

Article

Publication Date

12-2025

Identifier

DOI: 10.1038/s41372-025-02374-2; PMCID: PMC12717005

Abstract

OBJECTIVE: To categorize growth and correlate growth categories with morbidities in infants born before 32 weeks of gestation.

STUDY DESIGN: This retrospective study categorized weight growth by correlating mean growth velocity (GV) with growth trajectory z-score changes (ΔGTZ ), as measured using 2023 Postnatal Growth Charts for Preterm Infants. The associations between weight categories and morbidities were assessed.

RESULTS: Weight gain of infants without morbidities was categorized into three groups based on correlating ΔGTZ with mean GV: slower ( ΔGTZ < -0.1), in-parallel ( ΔGTZ -0.1 to 0.3), and faster ( ΔGTZ > 0.3). The proportions of infants with and without morbidities in these categories were evaluated across two distinct cohorts, revealing similar patterns. Both slower and faster growth were associated with bronchopulmonary dysplasia, while only slower growth was associated with retinopathy of prematurity.

CONCLUSION: Using the 2023 Postnatal Growth Charts for Preterm Infants, this study presents an alternative method for weight growth categorization.

Journal Title

Journal of perinatology : official journal of the California Perinatal Association

Volume

45

Issue

12

First Page

1758

Last Page

1764

MeSH Keywords

Humans; Retrospective Studies; Infant, Newborn; Growth Charts; Infant, Premature; Female; Male; Gestational Age; Weight Gain; Bronchopulmonary Dysplasia; Retinopathy of Prematurity

PubMed ID

40797023

Keywords

Retrospective Studies; Growth Charts; Gestational Age; Weight Gain; Bronchopulmonary Dysplasia; Retinopathy of Prematurity

Comments

This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Publisher's Link: https://www.nature.com/articles/s41372-025-02374-2

Included in

Pediatrics Commons

Share

COinS