Document Type

Article

Publication Date

11-6-2025

Identifier

DOI: 10.3389/fonc.2025.1645881; PMCID: PMC12631270

Abstract

INTRODUCTION: Acoustic neuroma (AN) is a benign tumor of the vestibulocochlear nerve, with increasing detection due to improved imaging. Treatment decisions are complex, requiring an individualized approach based on tumor size, location, growth rate, and patient-specific factors such as hearing and vestibular function.

RESULTS: Treatment options include observation, microsurgery, and stereotactic radiosurgery. Hearing preservation is prioritized in select cases using middle cranial fossa or retrosigmoid approaches, while translabyrinthine surgery is preferred for larger tumors or disabling dizziness. Stereotactic radiosurgery offers a non-invasive alternative but has variable long-term hearing outcomes and potential tumor regrowth. Vestibular rehabilitation is essential post-treatment, particularly after surgical resection.

DISCUSSION: Decision-making depends on patient age, tumor progression, and symptom severity. Younger patients with small tumors may benefit from early intervention to preserve hearing, while older patients with severe imbalance achieve better quality-of-life outcomes with surgery. Stereotactic radiosurgery remains an option for patients unable to undergo surgery, though its long-term efficacy and side effects require careful consideration. A multidisciplinary approach is essential to optimize treatment outcomes.

SUMMARY: AN management must be tailored to individual patient profiles. This review integrates current literature and expert clinical experience to guide otolaryngologists, neurologists, and oncologists in treatment planning. Future research should refine treatment algorithms and improve functional outcomes.

Journal Title

Front Oncol

Volume

15

First Page

1645881

Last Page

1645881

PubMed ID

41278265

Keywords

acoustic neuroma; gamma knife; middlecranial fossa; schwannoma; schwanomma surgery; stereotactic radiation; suboccipital approach; translabyrinthine approach

Comments

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Publisher's Link: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1645881/full

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