Comparison of Norwood shunt types: do the outcomes differ 6 years later?
Document Type
Article
Publication Date
7-1-2010
Identifier
DOI: 10.1016/j.athoracsur.2010.03.078
Abstract
BACKGROUND: A modification to the Norwood procedure involving a right ventricle-to-pulmonary artery (RV-PA) shunt may improve early postoperative outcomes. Concerns remain about the effect of the right ventriculotomy required with this shunt on long-term ventricular function.
METHODS: Between January 2000 and April 2005, 76 patients underwent the Norwood procedure, 35 with a modified Blalock-Taussig shunt (mBTS) and 41 with a RV-PA shunt. Patients were monitored until death or September 1, 2009, with an average follow-up of 6.8 years. Cardiac catheterization, echocardiograms, perioperative Fontan courses, and need for cardiac transplantation were compared between groups.
RESULTS: Cumulative survival was 63% (22 of 35) in the mBTS group vs 78% (32 of 41) in the RV-PA group (p = 0.14). Pre-Fontan echocardiography revealed poorer ventricular function in RV-PA patients (p = 0.03). Cardiac transplantation was required in 6 of 32 (19%) patients with a prior RV-PA shunt vs 1 of 23 (4%) in the mBTS group (p = 0.06). This results in an almost identical cumulative transplant-free survival between groups; 60% (21 of 35) in the mBTS group and 63% (26 of 41) in the RV-PA group (p = 0.95).
CONCLUSIONS: Neither shunt offers a clear survival advantage through an average follow-up of 6.8 years. The RV-PA shunt results in impaired late ventricular function that may result in an increased need for cardiac transplantation.
Journal Title
The Annals of thoracic surgery
Volume
90
Issue
1
First Page
31
Last Page
35
MeSH Keywords
Anastomosis, Surgical; Cardiac Surgical Procedures; Child; Child, Preschool; Follow-Up Studies; Fontan Procedure; Heart Defects, Congenital; Heart Ventricles; Humans; Hypoplastic Left Heart Syndrome; Pulmonary Artery
Recommended Citation
Graham, E. M., Zyblewski, S. C., Phillips, J. W., Shirali, G. S., Bradley, S. M., Forbus, G. A., Bandisode, V. M., Atz, A. M. Comparison of Norwood shunt types: do the outcomes differ 6 years later? The Annals of thoracic surgery 90, 31-35 (2010).