Integrating a Rapid Diagnostic Test and Antimicrobial Stewardship: Optimizing Discharge Antibiotics in Skin and Soft Tissue Infections.

Creator(s)

Diana Yu
Leslie Stach
Jason G. Newland, Children's Mercy Hospital
Rangaraj Selvarangan, Children's Mercy HospitalFollow
Jennifer Goldman, Children's Mercy Kansas CityFollow

Document Type

Article

Publication Date

12-1-2016

Identifier

DOI: 10.1097/INF.0000000000001332

Abstract

A rapid test to detect methicillin resistance in Staphylococcus aureus through the penicillin-binding protein 2a antigen was introduced for pediatric patients hospitalized for purulent skin and soft tissue infections. Integration of this test with physician education and stewardship guidance improved targeted antibiotic use for infections caused by methicillin-susceptible S. aureus (44%-80%, P < 0.001), including when final culture results were not available.

Journal Title

The Pediatric infectious disease journal

Volume

35

Issue

12

First Page

1362

Last Page

1364

MeSH Keywords

Adolescent; Adult; Anti-Bacterial Agents; Bacterial Typing Techniques; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Methicillin-Resistant Staphylococcus aureus; Penicillin-Binding Proteins; Pharmacy Service, Hospital; Reagent Kits, Diagnostic; Sensitivity and Specificity; Staphylococcal Skin Infections; Staphylococcus aureus; Young Adult

Keywords

Staph Infection; MRSA; antibiotics

Recommended Citation

Yu D, Stach L, Newland JG, Selvarangan R, Goldman J. Integrating a Rapid Diagnostic Test and Antimicrobial Stewardship: Optimizing Discharge Antibiotics in Skin and Soft Tissue Infections. Pediatr Infect Dis J. 2016;35(12):1362-1364. doi:10.1097/INF.0000000000001332