The GERD, The Bad, The Ugly: When Dosing Guidelines Ignore A BIG Problem
Download Transcript, Episode 97 (74 KB)
Valentina Shakhnovich, MD
Length of Episode
The medications used to treat gastroesophageal reflux (GERD) in children ignore one BIG factor – obesity. Obesity is a known risk factor for GERD in children, but the proton pump inhibitor (PPI) pantoprazole commonly used to treat GERD has no dosing guidelines for overweight and obese children.
Dr. Shakhnovich is here to explain that through her research, she has found that giving overweight children larger doses, a recently suggested practice with adults, could actually cause more harm than good and predispose children to unwanted side-effects from unintentional systemic overexposure to PPIs.
Smith, Michael and Shakhnovich, Valentina, "The GERD, The Bad, The Ugly: When Dosing Guidelines Ignore A BIG Problem" (2017). Transformational Pediatrics Podcast. 97.