Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation.

Creator(s)

Laura A. Wang
Daniel Gonzalez
J Steven Leeder, Children's Mercy HospitalFollow
Rachel F. Tyndale
Robin E. Pearce, Children's Mercy HospitalFollow
Daniel K. Benjamin
Gregory L. Kearns
Michael Cohen-Wolkowiez
Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee

Document Type

Article

Publication Date

2-1-2017

Identifier

PMCID: PMC5233579 DOI: 10.1002/jcph.797

Journal Title

Journal of clinical pharmacology

Volume

57

Issue

2

First Page

230

Last Page

234

MeSH Keywords

Anti-Infective Agents; Cohort Studies; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Infant, Newborn; Male; Metronidazole

Keywords

metabolism; metronidazole; neonates; pharmacokinetics; newborn babies

Recommended Citation

Wang LA, Gonzalez D, Leeder JS, et al. Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation. J Clin Pharmacol. 2017;57(2):230-234. doi:10.1002/jcph.797