Dental Manifestations and Management of a Pediatric Patient with Hypophosphatasia: Case Report and Literature Review

Authors

Dev Patel, Children's Mercy Kansas CityFollow
Robin Onikul, Children's Mercy HospitalFollow
Amy Burleson, Children's Mercy HospitalFollow
Brenda S Bohaty, Children's Mercy HospitalFollow
Jenna Sparks, Children's Mercy HospitalFollow
Neena Patel, Children's Mercy HospitalFollow

Publication Date

5-2024

Files

Abstract

Hypophosphatasia is a rare autosomal recessive disorder affecting the ALPL gene, which is involved in mineralization of bones and teeth. Given the importance of mineralization on proper tooth development, patients with hypophosphatasia present with numerous dental manifestations and require careful, coordinated care to maintain function and esthetics. This case report details a 9-year-old patient presenting to Children’s Mercy Kansas City Dental Clinic with complex medical history including hypophosphatasia, hypophosphatemic rickets, and developmental delay. The case report will include the patient’s clinical and radiographic presentation and will detail the patient’s treatment history. The presentation will also review the relevant scientific literature regarding hypophosphatasia and the clinical expectations for overall care.

Disciplines

Pediatric Dentistry and Pedodontics

Notes

Presented at the American Academy of Pediatric Dentistry (AAPD) 2024 Meeting; May 23-26; 2024; Toronto, Ontario, Canada.

Recommended Citation

Patel, Dev; Onikul, Robin; Burleson, Amy; Bohaty, Brenda S; Sparks, Jenna; and Patel, Neena, "Dental Manifestations and Management of a Pediatric Patient with Hypophosphatasia: Case Report and Literature Review" (2024). Posters. 393.
https://scholarlyexchange.childrensmercy.org/posters/393