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Works from 2021

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A Look Back at Bioethics: William L. Meadow, 1948-2019., John Lantos (Article)

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Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency., Juan Li, Wei-Te Lei, Peng Zhang, Franck Rapaport, Yoann Seeleuthner, Bingnan Lyu, Takaki Asano, Jérémie Rosain, Boualem Hammadi, Yu Zhang, Simon J Pelham, András N. Spaan, Mélanie Migaud, David Hum, Benedetta Bigio, Maya Chrabieh, Vivien Béziat, Jacinta Bustamante, Shen-Ying Zhang, Emmanuelle Jouanguy, Stephanie Boisson-Dupuis, Jamila El Baghdadi, Vishukumar Aimanianda, Katharina Thoma, Manfred Fliegauf, Bodo Grimbacher, Anne-Sophie Korganow, Carol J. Saunders, V Koneti Rao, Gulbu Uzel, Alexandra F. Freeman, Steven M. Holland, Helen C. Su, Charlotte Cunningham-Rundles, Claire Fieschi, Laurent Abel, Anne Puel, Aurélie Cobat, Jean-Laurent Casanova, Qian Zhang, and Bertrand Boisson (Article)

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COVID-19 Vaccination-Associated Myocarditis in Adolescents., Supriya S. Jain, Jeremy M. Steele, Brian Fonseca, Sihong Huang, Sanket Shah, Shiraz A. Maskatia, Sujatha Buddhe, Nilanjana Misra, Preeti Ramachandran, Lasya Gaur, Parham Eshtehardi, Shafkat Anwar, Neeru Kaushik, Frank Han, Nita Ray Chaudhuri, and Lars Grosse-Wortmann (Article)

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Development of a Health Disparities Index: Proof of Concept with Chest Radiography in Asthma., Kavita Parikh, Matt Hall, Sunitha V. Kaiser, Alexander H. Hogan, Jessica L. Bettenhausen, Michelle A. Lopez, and Marion R. Sills (Article)

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Diastolic Function and Ambulatory Hypertension in Children With Chronic Kidney Disease., Mark M. Mitsnefes, Yunwen Xu, Derek K. Ng, Garick Hill, Thomas Kimball, Susan L. Furth, and Bradley A. Warady (Article)

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Evaluation of Placentation and the Role of the Aryl Hydrocarbon Receptor Pathway in a Rat Model of Dioxin Exposure., Khursheed Iqbal, Stephen H. Pierce, Keisuke Kozai, Pramod Dhakal, Regan L. Scott, Katherine F Roby, Carrie A. Vyhlidal, and Michael J. Soares (Article)

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Explanatory Diagnoses Following Hospitalization for a Brief Resolved Unexplained Event., Risa Bochner, Joel S. Tieder, Erin Sullivan, Matt Hall, Allayne Stephans, Manoj K. Mittal, Nidhi Singh, Atima Delaney, Beth Harper, Nirav Shastri, Daniela Hochreiter, Mark I. Neuman, and BRIEF RESOLVED UNEXPLAINED EVENT RESEARCH AND QUALITY IMPROVEMENT NETWORK (Article)

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Health and Poverty of Rural Children: An Under-Researched and Under-Resourced Vulnerable Population., Jessica L. Bettenhausen, Courtney Winterer, and Jeffrey D. Colvin (Article)

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Healthcare System-to-System Cost Variability in the Care of Pediatric Abdominal Pain-Associated Functional Gastrointestinal Disorders., Michelle Livitz, Alec S. Friesen, Earl F. Glynn, Jennifer Verrill Schurman, Jennifer Colombo, and Craig A. Friesen (Article)

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Hippocampal epigenetic and insulin-like growth factor alterations in noninvasive versus invasive mechanical ventilation in preterm lambs., Xingrao Ke, Bohan Xing, Mar Janna Dahl, Jeremy Alvord, Robert A. McKnight, Robert H. Lane, and Kurt H. Albertine (Article)

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Job Satisfaction and Retention of an Advanced Practice Registered Nurse Fellowship Program., Cathy Cartwright (Article)

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Life Interrupted: Family Routines Buffer Stress during the COVID-19 Pandemic., Carolyn R. Bates, Laura M. Nicholson, Elizabeth M. Rea, Hannah A. Hagy, and Amy M. Bohnert (Article)

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Maternal plasma soluble neuropilin-1 is downregulated in fetal growth restriction complicated by abnormal umbilical artery Doppler: a pilot study., B Porter, D Maulik, S Babbar, T Schrufer-Poland, J Allsworth, S Q Ye, Daniel P. Heruth, and T Lei (Article)

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Methodologic Progress Note: A Clinician's Guide to Logistic Regression., Jessica L. Bettenhausen, Troy Richardson, Shoshana J. Herzig, and Matt Hall (Article)

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Methods for Detecting Pediatric Adverse Drug Reactions From the Electronic Medical Record., Lydia M. Joyner, Leah A. Alicea, Jennifer Goldman, Sarah Suppes, and Emma M. Tillman (Article)

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Obesity in asthma: Intricately linked and often overlooked., Kathyrn Kyler, Cassie Shipp, and Christine L. Schuler (Letter to the Editor)

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Physical and Cognitive Training to Enhance Intensive Care Unit Survivors' Cognition: A Mapping Review., Sue Lasiter, Matthew Chrisman, Britney Snodgrass, Marie Thompson, and Katherine Harmon (Article)

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Predictors and outcomes of heart block during surgical stage I palliation of patients with a single ventricle: A report from the NPC-QIC., Richard J. Czosek, Jeffrey B. Anderson, Shankar Baskar, Philip R. Khoury, Natalie Jayaram, and David S. Spar (Article)

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Qualitative indications for tracheostomy and chronic mechanical ventilation in patients with severe bronchopulmonary dysplasia., Sushmita Yallapragada, Rashmin C. Savani, Sara Mūnoz-Blanco, Joanne M. Lagatta, William E. Truog, Nicolas F M Porta, Leif D. Nelin, Huayan Zhang, Shilpa Vyas-Read, Robert DiGeronimo, Girija Natarajan, Erica Wymore, Beth Haberman, Joana Machry, Karin Potoka, Children’s Hospital Neonatal Consortium severe bronchopulmonary dysplasia subgroup, and Karna Murthy (Article)

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Reply. Rapid whole-genome sequencing in critically Ill children: shifting from unease to evidence, education, and equitable implementation, John Lantos (Response or Comment)

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Risk factors for anesthetic-related complications in pediatric patients with a newly diagnosed mediastinal mass., Neal Campbell, Alex Tsai, Brenton Reading, Marita Thompson, Janelle R. Noel-Macdonnell PhD, Randall Schwartz, and Paul Sheeran (Article)

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The Astonishingly Slow Progress Towards Surgical Anesthesia: Part I., Adam Booser (Article)

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The CNN Hip Accelerometer Posture (CHAP) Method for Classifying Sitting Patterns from Hip Accelerometers: A Validation Study., Mikael Anne Greenwood-Hickman, Supun Nakandala, Marta M. Jankowska, Dori E Rosenberg, Fatima Tuz-Zahra, John Bellettiere, Jordan A. Carlson, Paul R. Hibbing, Jingjing Zou, Andrea Z. Lacroix, Arun Kumar, and Loki Natarajan (Article)

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Prenatal delineation of coronary anatomy in dextro-transposition of great arteries, Geetha Haligheri, Chandrakant Patel, and Rukmini Komarlu (Article)

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Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12-18 Years - United States, June-September 2021., Samantha M. Olson, Margaret M. Newhams, Natasha B. Halasa, Ashley M. Price, Julie A. Boom, Leila C. Sahni, Katherine Irby, Tracie C. Walker, Stephanie P. Schwartz, Pia S. Pannaraj, Aline B. Maddux, Tamara T. Bradford, Ryan A. Nofziger, Benjamin J. Boutselis, Melissa L. Cullimore, Elizabeth H. Mack, Jennifer E. Schuster, Shira J. Gertz, Natalie Z. Cvijanovich, Michele Kong, Melissa A. Cameron, Mary A. Staat, Emily R. Levy, Brandon M. Chatani, Kathleen Chiotos, Laura D. Zambrano, Angela P. Campbell, Manish M. Patel, Adrienne G. Randolph, and Overcoming COVID-19 Investigators (Article)

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NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants., Stefan Graw, Marie Camerota, Brian S. Carter, Jennifer Helderman, Julie A. Hofheimer, Elisabeth C. McGowan, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Sheri A. DellaGrotta, Lynne M. Dansereau, James F. Padbury, Michael O'Shea, Barry M. Lester, Carmen J. Marsit, and Todd M. Everson (Article)

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Feasibility and Effectiveness of Recruiting Latinos in Decídetexto-A Smoking Cessation Clinical Trial from an Emergency Department Patient Registry, Evelyn Arana-Chicas, Francisco Cartujano-Barrera, Chinwe Ogedegbe, Edward F. Ellerbeck, Lisa Sanderson Cox, Kristi D. Graves, Francisco J. Diaz, Delwyn Catley, and Ana Paula Cupertino (Article)

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AHDC1 missense mutations in Xia-Gibbs syndrome, Michael M. Khayat, Jianhong Hu, Yunyun Jiang, He Li, Varuna Chander, Moez Dawood, Adam W. Hansen, Shoudong Li, Jennifer Friedman, Laura A. Cross, Emilia K. Bijlsma, Claudia A L Ruivenkamp, Francis H. Sansbury, Jeffrey W. Innis, Jessica Omark O'Shea, Qingchang Meng, Jill A. Rosenfeld, Kirsty McWalter, Michael F. Wangler, James R. Lupski, Jennifer E. Posey, David Murdock, and Richard A. Gibbs (Article)

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A Prospective Observational Study of Antihemophilic Factor (Recombinant) Prophylaxis Related to Physical Activity Levels in Patients with Hemophilia A in the United States (SPACE)., Barbara A. Konkle, Doris V. Quon, Leslie Raffini, Michael Recht, Vlad C. Radulescu, Shannon L. Carpenter, Amy L. Dunn, Mei Lu, and Maureen Watt (Article)

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Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis., Vivian Lee, Thomas D. Griffin, Yoko Suzuki-Horiuchi, Lily Wushanley, Yerin Kweon, Christine Marshall, Weijie Li, Elias Ayli, Adele Haimovic, Aliya Hines, and John T. Seykora (Article)

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Pharmacogenomics Factors Influencing the Effect of Risperidone on Prolactin Levels in Thai Pediatric Patients With Autism Spectrum Disorder., Yaowaluck Hongkaew, Andrea Gaedigk, Bob Wilffert, Roger Gaedigk, Wiranpat Kittitharaphan, Nattawat Ngamsamut, Penkhae Limsila, Apichaya Puangpetch, Rattanaporn Sukprasong, and Chonlaphat Sukasem (Article)

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Clinically Translatable Approaches of Inhibiting TGF-β to Target Cancer Stem Cells in TNBC., Andrew Sulaiman, Sarah McGarry, Sai Charan Chilumula, Rohith Kandunuri, and Vishak Vinod (Article)

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Expression of and correlational patterns among neuroinflammatory, neuropeptide, and neuroendocrine molecules from cerebrospinal fluid in cerebral palsy., Cory J. Goracke-Postle, Chantel C. Burkitt, Angela Panoskaltsis-Mortari, Michael Ehrhardt, George L. Wilcox, Patrick Graupman, Michael D. Partington, and Frank J. Symons (Article)

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Knowledge about juvenile idiopathic arthritis-associated uveitis: more frequent reminders are associated with higher patient and family uveitis knowledge., Ashley M. Cooper, Elaine R. Flanagan, Tova Ronis, Baruch Goldberg, Ashley K. Sherman, Chelsey Smith, Gary N. Holland, and CARRA Uveitis Workgroup (Article)

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Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia., P Narayanan, T-K Man, R B Gerbing, R Ries, A M Stevens, Y-C Wang, X Long, A S. Gamis, T Cooper, S Meshinchi, T A Alonzo, and M S Redell (Article)

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Access barriers to epinephrine autoinjectors for the treatment of anaphylaxis: A survey of practitioners., Punita Ponda, Anne F. Russell, Joyce E. Yu, Michael H. Land, Maria G. Crain, Kiran Patel, Jodi Shroba, and Panida Sriaroon (Article)

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Adverse Maternal Environment and Postweaning Western Diet Alter Hepatic CD36 Expression and Methylation Concurrently with Nonalcoholic Fatty Liver Disease in Mouse Offspring., Qi Fu, Paula E. North, Xingrao Ke, Yi-Wen Huang, Katie A. Fritz, Amber V. Majnik, and Robert H. Lane (Article)

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Association of routine school closures with child maltreatment reporting and substantiation in the United States; 2010-2017., Henry T. Puls, Matthew Hall, Terra Frazier, Kelly Schultz, and James Anderst (Article)

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Association of time of first corticosteroid treatment with bronchopulmonary dysplasia in preterm infants., Alain Cuna, Joanne M. Lagatta, Rashmin C. Savani, Shilpa Vyas-Read, William A. Engle, Rebecca S. Rose, Robert DiGeronimo, J Wells Logan, Michel Mikhael, Girija Natarajan, William E. Truog, Matthew Kielt, Karna Murthy, Isabella Zaniletti, Tamorah R. Lewis, and Children's Hospitals Neonatal Consortium (CHNC) Severe BPD Focus Group (Article)

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Brief Motivational Intervention to Improve Adolescent Sexual Health Service Uptake: A Pilot Randomized Controlled Trial in the Emergency Department., Melissa K. Miller, Delwyn Catley, Amber Adams, Vincent S. Staggs, M Denise Dowd, Stephani L. Stancil, Elizabeth Miller, Catherine L. Satterwhite, José Bauermeister, and Kathy Goggin (Article)

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Brivaracetam in treating epileptic encephalopathy and refractory focal epilepsies in patients under 14 years of age., Angelo Russo, Vittoria Cuteri, Lalit R. Bansal, Paolo Bonanni, Alberto Danieli, Antonella Pini, and Giuseppe Gobbi (Article)

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Centralized Reminder/Recall for Human Papillomavirus Vaccination: Findings From Two States-A Randomized Clinical Trial., Dennis Gurfinkel, Allison Kempe, Christina Albertin, Abigail Breck, Xinkai Zhou, Sitaram Vangala, Brenda Beaty, John Rice, Chi-Hong Tseng, Jonathan D. Campbell, Rebecca Valderrama, Cynthia Rand, Sharon Humiston, Heather Roth, Shivani Arora, and Peter Szilagyi (Article)

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Clinical Outcome and Antibiotic Dosing Differences by Weight in Children With Acute Osteomyelitis., Kathyrn Kyler, Brian R. Lee, Earl F. Glynn, Joel P Waddell, Mark A. Hoffman, and Jennifer Goldman (Article)

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Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents., Alon Geva, Manish M. Patel, Margaret M. Newhams, Cameron C. Young, Mary Beth F. Son, Michele Kong, Aline B. Maddux, Mark W. Hall, Becky J. Riggs, Aalok R. Singh, John S. Giuliano, Charlotte V. Hobbs, Laura L. Loftis, Gwenn E. McLaughlin, Stephanie P. Schwartz, Jennifer E. Schuster, Christopher J. Babbitt, Natasha B. Halasa, Shira J. Gertz, Sule Doymaz, Janet R. Hume, Tamara T. Bradford, Katherine Irby, Christopher L. Carroll, John K. McGuire, Keiko M. Tarquinio, Courtney M. Rowan, Elizabeth H. Mack, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Philip C. Spinella, Mary A. Staat, Katharine N. Clouser, Vijaya L. Soma, Heda Dapul, Mia Maamari, Cindy Bowens, Kevin M. Havlin, Peter M. Mourani, Sabrina M. Heidemann, Steven M. Horwitz, Leora R. Feldstein, Mark W. Tenforde, Jane W. Newburger, Kenneth D. Mandl, Adrienne G. Randolph, and Overcoming COVID-19 Investigators (Article)

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Evaluation of CPS compliance with legally required review of investigations by CAPs., Liza Murray, Joseph Yoder, Marissa Cantu, and James Anderst (Article)

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Factors associated with the absence of pharmacological treatment for common modifiable complications in children with chronic kidney disease., Yunwen Xu, Derek K. Ng, Susan L. Furth, Bradley A. Warady, and Mark M. Mitsnefes (Article)

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Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531, Jessica A. Pollard, Erin M. Guest, Todd A. Alonzo, Robert B. Gerbing, Mike R. Loken, Lisa Eidenschink Brodersen, E Anders Kolb, Richard Aplenc, Soheil Meshinchi, Susana C. Raimondi, Betsy Hirsch, and Alan S. Gamis (Article)

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Heterozygous HMGB1 loss-of-function variants are associated with developmental delay and microcephaly., Kévin Uguen, Kilannin Krysiak, Séverine Audebert-Bellanger, Sylvia Redon, Caroline Benech, Eléonore Viora-Dupont, Frederic Tran Mau-Them, Sophie Rondeau, Ibrahim Elsharkawi, Jorge L. Granadillo, Julie Neidich, Celia Azevedo Soares, Natáliya Tkachenko, Shivarajan M Amudhavalli, Kendra Engleman, Anne Boland, Jean-François Deleuze, Stéphane Bezieau, Sylvie Odent, Annick Toutain, Dominique Bonneau, Brigitte Gilbert-Dussardier, Laurence Faivre, Marlène Rio, Cedric Le Marechal, Claude Ferec, Elena Repnikova, and Yang Cao (Article)

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Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial., Martin L. Blakely; Jon E. Tyson; Kevin P. Lally; Susan R. Hintz; Barry Eggleston; David K. Stevenson; Gail E. Besner; Abhik Das; Robin K. Ohls; William E. Truog; Leif D. Nelin; Brenda B. Poindexter; Claudia Pedroza; Michele C. Walsh; Barbara J. Stoll; Rachel Geller; Kathleen A. Kennedy; Reed A. Dimmitt; Waldemar A. Carlo; C Michael Cotten; Abbot R. Laptook; Krisa P. Van Meurs; Kara L. Calkins; Gregory M. Sokol; Pablo J. Sanchez; Myra H. Wyckoff; Ravi M. Patel; Ivan D. Frantz; Seetha Shankaran; Carl T. D'Angio; Bradley A. Yoder; Edward F. Bell; Kristi L. Watterberg; Colin A. Martin; Carroll M. Harmon; Henry Rice; Arlet G. Kurkchubasche; Karl Sylvester; James C Y Dunn; Troy A. Markel; Diana L. Diesen; Amina M. Bhatia; Alan Flake; Walter J. Chwals; Rebeccah Brown; Kathryn D. Bass; Shawn D. St Peter; Christina M. Shanti; Walter Pegoli; David Skarda; Joel Shilyansky; David G. Lemon; Ricardo A. Mosquera; Myriam Peralta-Carcelen; Ricki F. Goldstein; Betty R. Vohr; Isabell B. Purdy; Abbey C. Hines; Nathalie L. Maitre; Roy J. Heyne; Sara B. DeMauro; Elisabeth C. McGowan; Kimberly Yolton; Howard Kilbride; Girija Natarajan; Kelley Yost; Sarah Winter; Tarah T. Colaizy; Matthew M. Laughon; Satyanarayana Lakshminrusimha; Rosemary D. Higgins; and Eunice Kennedy Shriver National Institute of Child Health, Human Development Neonatal Research Network (Article)

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Journal Club: Commentary on Capturing portable medical equipment disinfection data via an automated novel disinfection tracking system., Elizabeth Monsees and Timothy Wiemken (Editorial)

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Longitudinal associations between family conflict, parent engagement, and metabolic control in children with recent-onset type 1 diabetes., Hannah Case, David D. Williams, Shideh Majidi, Diana Ferro, Mark A. Clements, and Susana R. Patton (Article)

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Malnutrition diagnoses and associated outcomes in hospitalized patients: United States, 2018., Peggi Guenter, Ruba A. Abdelhadi, Pat Anthony, Allison Blackmer, Ainsley Malone, Jay M. Mirtallo, Wendy Phillips, and Helaine E. Resnick (Article)

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Mucosal eosinophils, mast cells, and intraepithelial lymphocytes in youth with rumination syndrome., Hunter J. Friesen, John Rosen, Christina M. Low Kapalu, Meenal Singh, Tracy Spaeth, Jose Cocjin, Craig A. Friesen, and Jennifer Verrill Schurman (Article)

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Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study., Melanie H. Jacobson, Yinxiang Wu, Mengling Liu, Kurunthachalam Kannan, Adela Jing Li, Morgan Robinson, Bradley A. Warady, Susan Furth, Howard Trachtman, and Leonardo Trasande (Article)

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Outcomes and Complications in Management of Congenital Myopathy Early-Onset Scoliosis., Lacey Magee, Joshua T. Bram, Jason B. Anari, Brandon Ramo, Oscar H. Mayer, Hiroko Matsumoto, Jaysson T. Brooks, Lindsay Andras, Robert Lark, Ryan Fitzgerald, Walter Truong, Ying Li, Lawrence Karlin, Richard M. Schwend, Stuart Weinstein, David Roye, Brian Snyder, John M. Flynn, Matthew Oetgen, John Smith, Patrick J. Cahill, and PSSG (Article)

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Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations., Lance H. Rodan, Rebecca C. Spillmann, Harley T. Kurata, Shawn M. Lamothe, Jasmine Maghera, Rami Abou Jamra, Anna Alkelai, Stylianos E Antonarakis, Isis Atallah, Omer Bar-Yosef, Frédéric Bilan, Kathrine Bjorgo, Xavier Blanc, Patrick Van Bogaert, Yoav Bolkier, Lindsay C. Burrage, Björn U. Christ, Jorge L. Granadillo, Patricia Dickson, Kirsten A. Donald, Christèle Dubourg, Aviva Eliyahu, Lisa Emrick, Kendra Engleman, Michaela Veronika Gonfiantini, Jean-Marc Good, Judith Kalser, Chiara Kloeckner, Guus Lachmeijer, Marina Macchiaiolo, Francesco Nicita, Sylvie Odent, Emily O'Heir, Xilma Ortiz-Gonzalez, Marta Pacio-Miguez, María Palomares-Bralo, Loren Pena, Konrad Platzer, Mathieu Quinodoz, Emmanuelle Ranza, Jill A Rosenfeld, Eliane Roulet-Perez, Avni Santani, Fernando Santos-Simarro, Ben Pode-Shakked, Cara Skraban, Rachel Slaugh, Andrea Superti-Furga, Isabelle Thiffault, Richard H. van Jaabrsveld, Marie Vincent, Hong-Gang Wang, Pia Zacher, Undiagnosed Diseases Network, Eric T. Rush, Geoffrey S Pitt, Ping Yee Billie Au, and Vandana Shashi (Article)

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Polygenic risk for neuroticism moderates response to gains and losses in amygdala and caudate: Evidence from a clinical cohort., Heekyeong Park, Katherine L. Forthman, Rayus Kuplicki, Teresa A. Victor, Tulsa 1000 Investigators, Hung-Wen Yeh, Wesley K. Thompson, and Martin P. Paulus (Article)

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Rare variants in KDR, encoding VEGF Receptor 2, are associated with tetralogy of Fallot., Doris Škorić-Milosavljević, Najim Lahrouchi, Fernanda M. Bosada, Gregor Dombrowsky, Simon G. Williams, Robert Lesurf, Fleur V Y Tjong, Roddy Walsh, Ihssane El Bouchikhi, Jeroen Breckpot, Enrique Audain, Aho Ilgun, Leander Beekman, Ilham Ratbi, Alanna Strong, Maximilian Muenke, Solveig Heide, Alison M. Muir, Mariam Hababa, Laura A. Cross, Dihong Zhou, T Pastinen, German Competence Network for Congenital Heart Defects, Elaine Zackai, Samir Atmani, Karim Ouldim, Najlae Adadi, Katharina Steindl, Anita Rauch, David Brook, Anna Wilsdon, Irene Kuipers, Nico A. Blom, Barbara J. Mulder, Heather C. Mefford, Boris Keren, Pascal Joset, Paul Kruszka, Isabelle Thiffault, Sarah E. Sheppard, Amy Roberts, Elisabeth M. Lodder, Bernard D. Keavney, Sally-Ann B. Clur, Seema Mital, Marc-Philip Hitz, Vincent M. Christoffels, Alex V. Postma, and Connie R. Bezzina (Article)

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Recovering from substance use disorders during the early months of the COVID-19 pandemic: A mixed-methods longitudinal study of women in Kansas City., Emily A. Hurley, Kimberly Pina, Victoria Cegielski, Janelle R. Noel-Macdonnell PhD, and Melissa K. Miller (Article)

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Scholarly Productivity in Clinical Pharmacology Amid Pandemic-Related Workforce Disruptions: Are Men and Women Affected Equally?, Alethea B. Gerding, Sharon J. Swan, Kimberly A. Brayer, and Susan M. Abdel-Rahman (Editorial)

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Sexual Health Behaviors and Pregnancy Risk Among Hospitalized Female Adolescents., Jane Alyce Hunt, Kimberly A Randell, Sarah Mermelstein, Melissa K. Miller, Ashley K. Sherman, Shirene Philipose, and Abbey R. Masonbrink (Article)

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Syndromic neurodevelopmental disorder associated with de novo variants in DDX23., William Burns, Lynne M. Bird, Delphine Heron, Boris Keren, Divya Ramachandra, Isabelle Thiffault, Florencia Del Viso, Shivarajan Amudhavalli, Kendra Engleman, Ilaria Parenti, Frank J. Kaiser, Jolanta Wierzba, Korbinian M. Riedhammer, Susanne Liptay, Neda Zadeh, Joseph Porrmann, Andrea Fischer, Sophie Gößwein, Heather M. McLaughlin, Aida Telegrafi, Katherine G. Langley, Richard Steet, Raymond J. Louie, and Michael J. Lyons (Article)

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The impact of botulinum injection for hospitalized children with Hirschsprung-associated enterocolitis., Wendy Jo Svetanoff, Joseph Lopez, Pablo Aguayo, Richard J. Hendrickson, Tolulope A. Oyetunji MD MPH, and Rebecca M. Rentea (Article)

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Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts., Michael G. Voss, David D. Cuthbertson, Mario M. Cleves, Ping Xu, Carmella Evans-Molina, Jerry P. Palmer, Maria J. Redondo, Andrea K. Steck, Markus Lundgren, Helena Larsson, Wayne V. Moore, Mark A. Atkinson, Jay M. Sosenko, Heba M. Ismail, and DPT-1 and TrialNet Study Groups (Article)

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Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children., Jason H. Greenberg, Alison G. Abraham, Yunwen Xu, Jeffrey R. Schelling, Harold I. Feldman, Venkata S. Sabbisetti, Joachim H. Ix, Manasi P. Jogalekar, Steven Coca, Sushrut S. Waikar, Michael G. Shlipak, Bradley A. Warady, Ramachandran S. Vasan, Paul L. Kimmel, Joseph V. Bonventre, Michelle Denburg, Chirag R. Parikh, Susan Furth, CKD Biomarkers Consortium, and CKD Biomarker consortium (Article)

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Using learning management software data to compare students' actual and self-reported viewing of video lectures., JoAnna M. Scott, Brenda S Bohaty, and Cynthia C. Gadbury-Amyot (Article)

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CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group., Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda Leonti, Jenny L. Smith, Tiffany A. Hylkema, William G. Woods, Todd M. Cooper, E Anders Kolb, A S. Gamis, Richard Aplenc, Todd A. Alonzo, and Soheil Meshinchi (Article)

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COVID-19, Telehealth, and Pediatric Integrated Primary Care: Disparities in Service Use., Ayanda Chakawa, Leslee Belzer, Trista Perez-Crawford, and Hung-Wen Yeh (Article)

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Use of large scale EHR data to evaluate A1c utilization among sickle cell disease patients., Shivani Sivasankar, An-Lin Cheng, Ira M Lubin, Kamani Lankachandra, and Mark A. Hoffman (Article)

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Precision dosing of vancomycin: in defence of AUC-guided therapy in children., Mark E. Murphy, Sonya Tang Girdwood, Jennifer Goldman, Marc H. Scheetz, and Kevin J. Downes (Article)

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Academic Medical Center Visits by Adolescents Preceding Emergency Department Care for Suicidal Ideation or Suicide Attempt., Arjun Sarin, Gregory P. Conners, Shayla Sullivant, Joan Giovanni, Ashley K. Sherman, Christina Zanaboni, and Kimberly A Randell (Article)

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Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain., Afrida Rahman-Enyart, Wenbin Yang, Ryan E. Yaggie, Bryan A. White, Michael Welge, Loretta Auvil, Matthew Berry, Colleen Bushell, John Rosen, Charles N. Rudick, Anthony J. Schaeffer, and David J. Klumpp (Article)

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APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis., Jarcy Zee, Michelle T. McNulty, Jeffrey B. Hodgin, Olga Zhdanova, Sangeeta Hingorani, Jonathan Ashley Jefferson, Keisha L. Gibson, Howard Trachtman, Alessia Fornoni, Katherine M. Dell, Heather N. Reich, Serena Bagnasco, Larry A. Greenbaum, Richard A. Lafayette, Debbie S. Gipson, Elizabeth Brown, Matthias Kretzler, Gerald Appel, Kamalanathan K. Sambandam, Katherine R. Tuttle, Dhruti Chen, Meredith A. Atkinson, Marie C. Hogan, Frederick J. Kaskel, Kevin E. Meyers, John O'Toole, Tarak Srivastava, Christine B. Sethna, Michelle A. Hladunewich, J J Lin, Cynthia C. Nast, Vimal K. Derebail, Jiten Patel, Suzanne Vento, Lawrence B. Holzman, Ambarish M. Athavale, Sharon G. Adler, Kevin V. Lemley, John C. Lieske, Jonathan J. Hogan, Crystal A. Gadegbeku, Fernando C. Fervenza, Chia-Shi Wang, Raed Bou Matar, Pamela Singer, Jeffrey B. Kopp, Laura Barisoni, and Matthew G. Sampson (Article)

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A System-Wide Hospital Child Maltreatment Patient Safety Program., Jennifer B. Hansen, Amy Terreros, Ashley K. Sherman, Andrew Donaldson, and James Anderst (Article)

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Biomarkers, Imaging and Patient Reported Outcomes in The Chronic Kidney Disease in Children Study., Susan Furth and Bradley A. Warady (Editorial)

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Comparative in vitro effectiveness of ceftolozane/tazobactam against pediatric gram-negative drug-resistant isolates, Neena Kanwar, Dithi Banerjee, Christopher J. Harrison, Jason G. Newland, Xuan Qin, Danielle M. Zerr, Theoklis Zaoutis, and Rangaraj Selvarangan (Article)

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Continuous Glucose Monitoring Decreases Hypoglycemia Avoidance Behaviors, but Not Worry in Parents of Youth With New Onset Type 1 Diabetes., Erin M. Youngkin, Shideh Majidi, Amy E. Noser, Kelly R. Stanek, Mark A. Clements, and Susana R. Patton (Article)

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Effect of Training Pediatric Clinicians in Human Papillomavirus Communication Strategies on Human Papillomavirus Vaccination Rates: A Cluster Randomized Clinical Trial., Peter G. Szilagyi, Sharon Humiston, Alisa J. Stephens-Shields, Russell Localio, Abigail Breck, Mary Kate Kelly, Margaret Wright, Robert W. Grundmeier, Christina Albertin, Laura P. Shone, Jennifer Steffes, Cynthia M. Rand, Chloe Hannan, Dianna E. Abney, Greta McFarland, Gerald F. Kominski, Brayan V. Seixas, and Alexander G. Fiks (Article)

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Factors Related to Serious Safety Events in a Children's Hospital Patient Safety Collaborative., Stephanie Burrus, Matthew Hall, Emily Tooley, Kate Conrad, Jessica L. Bettenhausen, and Carol Kemper (Article)

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Family rules, routines, and caregiver distress during the first year of pediatric cancer treatment., Carolyn R. Bates, Isabella K Pallotto, Rachel M Moore, Mirae J. Fornander, Lynne M Covitz, and Meredith Dreyer (Article)

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Hungry Bone Syndrome Secondary to Subtotal Thyroidectomy in A Patient With Thyrotoxicosis., Zi Guo, Liling Zhao, Yanhong Xie, Yun Yan, and Zhaohui Mo (Article)

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Identifying HbA1c trajectories and modifiable risk factors of trajectories in 5- to 9-year-olds with recent-onset type 1 diabetes from the United States., Susana R. Patton, Keith Feldman, Shideh Majidi, Amy Noser, and Mark A. Clements (Article)

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Impact of an institution-designed algorithm for the management of dislodged gastrostomy tubes., Obiyo O. Osuchukwu, Charlene Dekonenko, Wendy Jo Svetanoff, Neal Talukdar, Lisa L. Schroeder, Jeff Michael, Jacqueline Bartlett, and Jason D. Fraser (Article)

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Implementation of a Scalable Family-Based Behavioral Treatment for Childhood Obesity Delivered through Primary Care Clinics: Description of the Missouri Childhood Obesity Research Demonstration Study Protocol., Denise E. Wilfley, Lauren A. Fowler, Sarah Hampl, Meredith Dreyer, Amanda E. Staiano, Andrea K. Graham, Anne Claire Grammer, Lisa Nelson, Jordan A. Carlson, Derek S. Brown, Sherri Gabbert, Kelly Springstroh, Fanice Thomas, Melissa Ramel, Robinson Welch, William Johnson, and MO-CORD Study Group (Article)

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Implementation of School Remote Drop-off Walking Programs: Results from Qualitative Interviews., Carolina M Bejarano, MacKenzie N Koester, Chelsea Steel, and Jordan A. Carlson (Article)

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IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial): Randomized Clinical Trial of Monotherapy Versus Multi-drug Antibiotic Therapy., Justin Lee, Erin M. Garvey, Nikkida Bundrant, Angela Hargis-Villanueva, Paul Kang, Obiyo O. Osuchukwu, Charlene Dekonenko, Wendy Jo Svetanoff, Shawn D. St Peter, Benjamin Padilla, and Daniel Ostlie (Article)

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Justice System Involvement Among Adolescents in the Emergency Department., Vivek Dubey, Kimberly A Randell, Abbey R. Masonbrink, Michelle L. Pickett, Ashley K. Sherman, Megha Ramaswamy, and Melissa K. Miller (Article)

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Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis., Kevin M. Johnson, Ryan T. Fischer, Gerald J. Holtmann, Ayesha Shah, Leina Alrabadi, and Peter Lewindon (Letter to the Editor)

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Management and outcomes for long-segment Hirschsprung disease: A systematic review from the APSA outcomes and evidence based practice committee., Akemi L. Kawaguchi, Yigit S. Guner, Stig Sømme, Alexandria C. Quesenberry, L Grier Arthur, Juan E. Sola, Cynthia D. Downard, Rebecca M. Rentea, Patricia A. Valusek, Caitlin A. Smith, Mark B. Slidell, Robert L. Ricca, Roshni Dasgupta, Elizabeth Renaud, Doug Miniati, Jarod McAteer, Alana L. Beres, Julia Grabowski, Shawn D. St Peter, Ankush Gosain, and American Pediatric Surgical Association Outcomes and Evidence-Based Practice (OEBP) Committee (Article)

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Maternal parechovirus A (PeV-A) shedding, serostatus, and the risk of central nervous system PeV-A infections in infants., J Michael Klatte, Christopher J. Harrison, Brian Pate, Mary Ann Queen, Jesica Neuhart, Mary Anne Jackson, and Rangaraj Selvarangan (Article)

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Meditation and Mindfulness in Pregnancy and Postpartum: A Review of the Evidence., Shilpa Babbar, Alejandro J. Oyarzabal, and Esteban A. Oyarzabal (Article)

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Mortality in Children Treated With Maintenance Peritoneal Dialysis: Findings From the International Pediatric Peritoneal Dialysis Network Registry., Sophie Ploos van Amstel, Marlies Noordzij, Dagmara Borzych-Duzalka, Nicholas C. Chesnaye, Hong Xu, Lesley Rees, Il-Soo Ha, Zenaida L. Antonio, Nakysa Hooman, William Wong, Karel Vondrak, Yok Chin Yap, Hiren Patel, Maria Szczepanska, Sara Testa, Monica Galanti, Jameela A. Kari, Charlotte Samaille, Sevcan A. Bakkaloglu, Wai-Ming Lai, Luisa Fernanda Rojas, Mabel Sandoval Diaz, Biswanath Basu, Alicia Neu, Bradley A. Warady, Kitty J. Jager, and Franz Schaefer (Article)

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Neurocognition in Pediatric Chronic Kidney Disease: A Review of Data From the Chronic Kidney Disease in Children (CKiD) Study., Rebecca J. Johnson and Lyndsay A. Harshman (Article)

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Neurodevelopmental outcomes in preterm infants with retinopathy of prematurity., Hao Tan, Patricia Blasco, Tamorah R. Lewis, Susan Ostmo, Michael F. Chiang, and John Peter Campbell (Article)

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Normal or reactive minor cell populations in bone marrow and peripheral blood mimic minimal residual leukemia by flow cytometry., Weijie Li, Ruth Morgan, Roxanne Nieder, Sa Truong, Sahibu Sultan M Habeebu, and Atif Ahmed (Article)

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Outcomes following perinatal palliative care consultation: a retrospective review., Megan H. Tucker, Kelstan Ellis, and Jennifer Linebarger (Article)

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Pharmacogene Variation Consortium: A Global Resource and Repository for Pharmacogene Variation., Andrea Gaedigk, Scott T. Casey, Michelle Whirl-Carrillo, Neil A. Miller, and Teri E. Klein (Article)

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PharmVar GeneFocus: CYP2C9., Katrin Sangkuhl, Karla Claudio-Campos, Larisa H. Cavallari, Jose A G Agundez, Michelle Whirl-Carrillo, Jorge Duconge, Andria L. Del Tredici, Mia Wadelius, Mariana Rodrigues Botton, Erica L. Woodahl, Stuart A. Scott, Teri E. Klein, Victoria M. Pratt, Ann K. Daly, and Andrea Gaedigk (Article)

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Post-operative arrhythmias in patients with hypoplastic left heart syndrome and anatomic variants: incidence, type, and course., Muluneh A. Yimer, Svjetlana Tisma-Dupanovic, Lindsey Malloy-Walton, Diana Connelly, Janelle R. Noel-Macdonnell PhD, James O' Brien, and John Papagiannis (Article)

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Preoperative resource utilization prior to minimally invasive repair of pectus excavatum., Yangyang R. Yu, Richard Sola, Abdur R. Jamal, Tyler C. Friske, Huirong Zhu, Eric Rosenfeld, Mark V. Mazziotti, Shawn D. St Peter, and Sohail R. Shah (Article)