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Works from 2022

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NanoString Digital Molecular Profiling of Protein and microRNA in Rhabdomyosarcoma., Atif Ahmed, Midhat S. Farooqi, Sahibu Sultan M Habeebu, Elizabeth Gonzalez, Terrie Flatt, Ashley L. Wilson, and Frederic G. Barr (Article)

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Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin., Mohamed A.A. Alalem, Mrinalini Bhosale, Atul Ranjan, Satomi Yamamoto, Atsushi Kaida, Shigeto Nishikawa, Alejandro Parrales, Sana Farooki, Shrikant Anant, Subhash Padhye, and Tomoo Iwakuma (Article)

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Health-related quality of life and fatigue in children and adults with pyruvate kinase deficiency., Hanny Al-Samkari, Eduard J. van Beers, D Holmes Morton, Stefan W. Eber, Satheesh Chonat, Kevin H M Kuo, Nina Kollmar, Heng Wang, Vicky R. Breakey, Sujit Sheth, Mukta Sharma, Peter W. Forbes, Robert J. Klaassen, and Rachael F. Grace (Article)

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Subtypes of childhood insomnia., Baha Al-Shawwa MD, Mukta Sharma, and David G. Ingram MD (Letter to the Editor)

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Terrible twos: intravenous iron ameliorates a toddler's iron deficiency and sleep disturbance, Baha Al-Shawwa MD, Mukta Sharma, and David G. Ingram MD (Article)

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Symptom Profiles of Adolescents and Young Adults in Active Cancer Treatment by Diagnostic Groups., Suzanne Ameringer, R K Elswick, Kristin Stegenga, Catherine Fiona Macpherson, Jeanne M. Erickson, and Lauri Linder (Article)

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Evaluation for Bleeding Disorders in Suspected Child Abuse., James Anderst; Shannon L. Carpenter; Thomas C. Abshire; Emily Killough; AAP SECTION ON HEMATOLOGY/ONCOLOGY, THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY, THE AAP COUNCIL ON CHILD ABUSE AND NEGLECT; Eneida A. Mendonca; Stephen M. Downs; Section on Hematology/Oncology executive committee, 2020–2021; Cynthia Wetmore; Carl Allen; David Dickens; James Harper; Zora R. Rogers; Juhi Jain; Anne Warwick; Amber Yates; Jeffrey Hord; Jeffrey Lipton; Hope Wilson; Suzanne Kirkwood; Council on Child Abuse and Neglect, 2020–2021; Suzanne B. Haney; Andrea Gottsegen Asnes; Amy R. Gavril; Rebecca Greenlee Girardet; Nancy Heavilin; Amanda Bird Hoffert Gilmartin; Antoinette Laskey; Stephen A. Messner; Bethany Anne Mohr; Shalon Marie Nienow; Norell Rosado; Council on Child Abuse and Neglect executive committee members; Sheila M. Idzerda; Lori A. Legano; Anish Raj; Andrew P. Sirotnak; Heather C. Forkey; Council on Foster Care, Adoption and Kinship Care; Brooks Keeshin; American Academy of Child and Adolescent Psychiatry; Jennifer Matjasko; Centers for Disease Control and Prevention; Heather Edward; Müge Chavdar; American Society of Pediatric Hematology/Oncology Board of Trustees, 2020–2021; Jorge Di Paola; Patrick Leavey; Doug Graham; Caroline Hastings; Nobuko Hijiya; Jeffrey Hord; Dana Matthews; Betty Pace; Maria C Velez; Dan Wechsler; Amy Billett; Linda Stork; and Ryan Hooker (Article)

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Adolescent and young adult (AYA) versus pediatric patients with acute leukemia have a significantly increased risk of acute GVHD following unrelated donor (URD) stem cell transplantation (SCT): the Children's Oncology Group experience., Jeffrey R. Andolina, Yi-Cheng Wang, Lingyun Ji, David R. Freyer, John E. Levine, Michael A. Pulsipher, Alan S. Gamis, Richard Aplenc, Michael E. Roth, Lauren Harrison, and Mitchell S. Cairo (Article)

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Demographics in Children Presenting With Acute Neurologic Deficits Concerning for Stroke: An Evaluation of the Stroke Alert Process., Tiffany Barkley, Roha Khalid, Mukta Sharma, Ashley K. Sherman, and Jennifer Flint (Article)

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Informing Parents as Caregivers With a Symptom Assessment App Developed for Children With Cancer., Katherine M. Bernier Carney, Kristin Stegenga, and Lauri A. Linder (Article)

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Evaluating for Suspected Child Abuse: Conditions That Predispose to Bleeding., Shannon L. Carpenter; Thomas C. Abshire; Emily Killough; James Anderst; and AAP SECTION ON HEMATOLOGY/ONCOLOGY, THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, and the AAP COUNCIL ON CHILD ABUSE AND NEGLECT (Article)

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Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia., Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-Hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W. Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-Yang Ding, Stephen P. Hunger, Carolyn A. Felix, Hao Wu, Patrick A. Brown, Erin M. Guest, David M. Barrett, Kathrin M. Bernt, and Kai Tan (Article)

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Human Peripheral Blood Mononucleocyte Derived Myeloid Committed Progenitor Cells Mitigate H-ARS by Exosomal Paracrine Signal., Rishi Man Chugh, Payel Bhanja, Ximena Diaz Olea, Fang Tao, Kealan Schroeder, Ryan Zitter, Tanu Arora, Harsh Pathak, Bruce F. Kimler, Andrew K. Godwin, John M. Perry, and Subhrajit Saha (Article)

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Genomic answers for children: Dynamic analyses of >1000 pediatric rare disease genomes., Ana S A Cohen, Emily G. Farrow, Ahmed Abdelmoity, Joseph Alaimo, Shivarajan Manickavasagam Amudhavalli, John Anderson, Lalit R. Bansal, Lauren E. Bartik, Primo Baybayan, Bradley Belden, Courtney D. Berrios, Rebecca L. Biswell, Pawel Buczkowicz, Orion Buske, Shreyasee Chakraborty, Warren A. Cheung, Keith A. Coffman, Ashley M. Cooper, Laura A. Cross, Tom Curran, Thuy Tien T. Dang, Mary M. Elfrink, Kendra Engleman, Erin Day Fecske, Cynthia Fieser, Keely M. Fitzgerald, Emily Fleming, Randi N. Gadea, Jennifer L. Gannon, Rose N. Gelineau-Morel, Margaret Gibson, Jeffrey Goldstein, Elin Grundberg, Kelsee Halpin, Brian S. Harvey, Bryce Heese, Wendy Hein, Suzanne M. Herd, Susan Starling Hughes, Mohammed Ilyas, Jill Jacobson, Janda L. Jenkins, Shao Jiang, Jeffrey J. Johnston, Kathryn Keeler, Jonas Korlach, Jennifer Kussman, Christine Lambert, Caitlin E. Lawson, Jean-Baptist LePichon, J Steven Leeder, Vicki C. Little, Daniel A. Louiselle, Michael Lypka, Brittany D. McDonald, Neil Miller, Ann Modrcin, Annapoorna Nair, Shelby H. Neal, Christopher M. Oermann, Donna M. Pacicca, Kailash Pawar, Nyshele L. Posey, Nigel Price, Laura M B Puckett, Julio Quezada, Nikita Raje, William J. Rowell, Eric T. Rush, Venkatesh Sampath, Carol J. Saunders, Caitlin Schwager, Richard M. Schwend, Elizabeth Shaffer, Craig Smail, Sarah E. Soden, Meghan Strenk, Bonnie Sullivan, Brooke Sweeney, Jade B. Tam-Williams, Adam Walter, Holly Welsh, Aaron M. Wenger, Laurel K. Willig, Yun Yan, Scott T. Younger, Dihong Zhou, Tricia N. Zion, Isabelle Thiffault, and Tomi Pastinen (Article)

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MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation., Jennifer Crow, Glenson Samuel, Emily G. Farrow, Margaret Gibson, Jeffrey J. Johnston, Erin M. Guest, Neil Miller, Dong Pei, Devin Koestler, Harsh Pathak, Xiaobo Liang, Cooper Mangels, and Andrew K. Godwin (Article)

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Improving infectious adverse event reporting for children and adolescents enrolled in clinical trials for acute lymphoblastic leukemia: A report from the Children's Oncology Group., Caitlin W. Elgarten, Joel Thompson, Anne Angiolillo, Zhiguo Chen, Susan Conway, Meenakshi Devidas, Sumit Gupta, John A. Kairalla, Jennifer L. McNeer, Maureen M. O'Brien, Karen R. Rabin, Rachel E. Rau, Susan R. Rheingold, Cindy Wang, Charlotte Wood, Elizabeth A. Raetz, Mignon L. Loh, Sarah Alexander, and Tamara P. Miller (Article)

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Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation., Abdelrahman H. Elsayed, Xueyuan Cao, Amit K. Mitra, Huiyun Wu, Susana Raimondi, Christopher Cogle, Zeina Al-Mansour, Raul C. Ribeiro, Alan S. Gamis, Edward Anders Kolb, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi, Jeffrey Rubnitz, Stanley Pounds, and Jatinder K. Lamba (Article)

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Novel Oncogenic PDGFRB Variant in Severe Infantile Myofibromatosis With Response to Imatinib Using Therapeutic Drug Monitoring, Abbey Elsbernd, Boutaina Boulouadnine, Atif Ahmed, Midhat S. Farooqi, Tracy L. Sandritter, Valentina Shakhnovich, Darius Blanding, Jean-Baptiste Demoulin, and Joel Thompson (Article)

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A phase IV, multicentre, open-label study of emicizumab prophylaxis in people with haemophilia A with or without FVIII inhibitors undergoing minor surgical procedures., Miguel Escobar, Amy Dunn, Doris Quon, Ben Trzaskoma, Lucy Lee, Richard H. Ko, and Shannon L. Carpenter (Article)

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Safety and efficacy of voxelotor in pediatric patients with sickle cell disease aged 4 to 11 years., Jeremie H. Estepp, Ram Kalpatthi, Gerald Woods, Sara Trompeter, Robert I. Liem, Kacie Sims, Adlette Inati, Baba P D Inusa, Andrew Campbell, Connie Piccone, Miguel R. Abboud, Kim Smith-Whitley, Sandra Dixon, Margaret Tonda, Carla Washington, Noelle M. Griffin, and Clark Brown (Article)

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Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy., Vanessa A. Fabrizio, Jaap Jan Boelens, Audrey Mauguen, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vasant Chinnabhandar, Michael Kunicki, A Yasemin Goksenin, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz, and Kevin J. Curran (Article)

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Tisagenlecleucel Outcomes in Relapsed/Refractory Extramedullary ALL: A Pediatric Real World CAR Consortium Report., Vanessa A. Fabrizio, Christine L. Phillips, Adam Lane, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly L. Pacenta, Jenna Rossoff, Heather Stefanski, Julie-An An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vasant Chinnabhandar, Michael Kunicki, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, and Liora M. Schultz (Article)

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A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials., Mohammed O. Gbadamosi, Vivek M. Shastri, Abdelrahman H. Elsayed, Rhonda Ries, Oluwaseyi Olabige, Nam H K Nguyen, Angelica De Jesus, Yi-Cheng Wang, Alice Dang, Betsy A. Hirsch, Todd A. Alonzo, Alan S. Gamis, Soheil Meshinchi, and Jatinder K. Lamba (Article)

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Cytarabine dose reduction in patients with low-risk acute myeloid leukemia: A report from the Children's Oncology Group., Kelly D. Getz, Todd A. Alonzo, Lillian Sung, Soheil Meshinchi, Robert B. Gerbing, Susana Raimondi, Betsy Hirsch, Michael Loken, Lisa Eidenschink Brodersen, Samir Kahwash, John Choi, E Anders Kolb, Alan S. Gamis, and Richard Aplenc (Article)

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Outstanding outcomes in infants with KMT2A-germline acute lymphoblastic leukemia treated with chemotherapy alone: results of the Children's Oncology Group AALL0631 trial, Erin M. Guest, John A. Kairalla, Joanne M. Hilden, ZoAnn E. Dreyer, Andrew J. Carroll, Nyla A. Heerema, Cindy Y. Wang, Meenakshi Devidas, Lia Gore, Wanda L. Salzer, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Michael Borowitz, Mignon L. Loh, Stephen P. Hunger, and Patrick A. Brown (Letter to the Editor)

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Randomized Clinical Trial of a Self-care and Communication Intervention for Parents of Adolescent/Young Adults Undergoing High-Risk Cancer Treatment: A Report From the Children's Oncology Group., Joan E. Haase, Kristin Stegenga, Sheri L. Robb, Mary C. Hooke, Debra S. Burns, Patrick O. Monahan, Timothy E. Stump, Amanda K. Henley, Paul R. Haut, Brooke Cherven, Lona Roll, Anne-Marie Langevin, Rita H. Pickler, Karen Albritton, DeAnna Hawkins, Erin Osterkamp, Pauline Mitby, Jackie Smith, Virginia R. Diaz, Erica Garcia-Frausto, and Margo Moore (Article)

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Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults., Melissa R. Hines, Tatiana von Bahr Greenwood, Gernot Beutel, Karin Beutel, J Allyson Hays, AnnaCarin Horne, Gritta Janka, Michael B. Jordan, Jan A M van Laar, Gunnar Lachmann, Kai Lehmberg, Rafal Machowicz, Päivi Miettunen, Paul La Rosée, Bita Shakoory, Matt S. Zinter, and Jan-Inge Henter (Article)

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Clinical relevance of proteomic profiling in de novo pediatric acute myeloid leukemia: a Children's Oncology Group study, Fieke W. Hoff, Anneke D. Van Dijk, Yihua Qiu, Chenyue W. Hu, Rhonda E. Ries, Andrew Ligeralde, Gaye N. Jenkins, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Amina A. Qutub, Eveline S J M De Bont, Terzah M. Horton, and Steven M. Kornblau (Article)

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Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia., Benjamin J. Huang, Jenny L. Smith, Jason E. Farrar, Yi-Cheng Wang, Masayuki Umeda, Rhonda E. Ries, Amanda R. Leonti, Erin Crowgey, Scott N. Furlan, Katherine Tarlock, Marcos Armendariz, Yanling Liu, Timothy I. Shaw, Lisa Wei, Robert B. Gerbing, Todd M. Cooper, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Jeffrey Rubnitz, Jing Ma, Jeffery M. Klco, Xiaotu Ma, Todd A. Alonzo, Timothy Triche, and Soheil Meshinchi (Article)

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Intravenous iron therapy in the pediatric sleep clinic: a single institution experience., David G. Ingram MD, Baha Al-Shawwa MD, Lourdes M. DelRosso, and Mukta Sharma (Article)

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Symptomatic pulmonary embolus after catheter removal in children with catheter related thrombosis: A report from the CHAT Consortium., Julie Jaffray, Lisa Baumann Kreuziger, Brian Branchford, Choo Phei Wee, E Vincent S. Faustino, Neil A. Zakai, Stacy E. Croteau, Michael Silvey, John H. Fargo, James D. Cooper, Nihal Bakeer, Amy Stillings, Emily Krava, Guy Young, and Neil A. Goldenberg (Article)

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A New Risk Assessment Model for Hospital-Acquired Venous Thromboembolism in Critically Ill Children: A Report From the Children's Hospital-Acquired Thrombosis Consortium., Julie Jaffray, Arash Mahajerin, Brian Branchford, Anh Thy H. Nguyen, E Vincent S. Faustino, Michael Silvey, Stacy E. Croteau, John H. Fargo, James D. Cooper, Nihal Bakeer, Neil A. Zakai, Amy Stillings, Emily Krava, Ernest K. Amankwah, Guy Young, and Neil A. Goldenberg (Article)

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Music Therapy for Children with Oncology & Hematological Conditions and Their Families: Advancing the Standards of Psychosocial Care., David Knott, Caitlin Krater, Jessica MacLean, Kim Robertson, Kristin Stegenga, and Sheri L Robb (Article)

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Hemostatic and Thrombotic Considerations in the Diagnosis and Management of Childhood Arterial Ischemic Stroke: A Narrative Review., Riten Kumar, Lisa R. Sun, Vilmarie Rodriguez, Amanda Sankar, Mukta Sharma, Avner Meoded, Leonardo R. Brandão, and Neil A. Goldenberg (Article)

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Assessment of Arsenic Trioxide and All-trans Retinoic Acid for the Treatment of Pediatric Acute Promyelocytic Leukemia: A Report From the Children's Oncology Group AAML1331 Trial., Matthew A. Kutny, Todd A. Alonzo, Oussama Abla, Madhvi Rajpurkar, Robert B. Gerbing, Yi-Cheng Wang, Betsy A. Hirsch, Susana Raimondi, Samir Kahwash, Kristina K. Hardy, Steven Hardy, Soheil Meshinchi, Alan S. Gamis, Edward A. Kolb, James H. Feusner, and John Gregory (Article)

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Clinical predictors of invasive fungal rhinosinusitis in a tertiary pediatric hospital., Brennan Lee, Dwight Yin, Keith August, Janelle R. Noel-Macdonnell PhD, Meghan Tracy, and Daniel R. Jensen (Article)

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Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness., Changzheng Li, Binghuo Wu, Yishan Li, Yaxi Liu, Jin Wang, Jiayi Xie, Xi Xu, Xiaobin Tian, Zhitao Ye, Jingjing Guan, Jie Chen, Siyu Xie, Baolin Zhang, Boyong Cai, Qianhao Wang, Haopeng Yu, Tian Lan, Cheuk Him Man, Xunlei Kang, Pengxu Qian, John M. Perry, Aibin He, Linjia Jiang, and Meng Zhao (Article)

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Symptoms and daily experiences reported by children with cancer using a game-based app., Lauri A. Linder, Amy Newman, Katherine M. Bernier Carney, Sarah Wawrzynski, Kristin Stegenga, Yin-Shun Chiu, Se-Hee Jung, Eli Iacob, Melina Lewis, Caitlin Linder, Kaitlyn Fox, and Roger Altizer (Article)

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Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single-institutional experience., Sarah E. Mc Dermott, Chandni Dargan, Elizabeth Gonzalez, Lejla Music Aplenc, Terrie Flatt, and Nazia Iqbal (Article)

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Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia., Amy Moskop, Lauren Pommert, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Steve P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Erin M. Guest, Erin H. Breese, and Liora M. Schultz (Article)

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DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen., Shigeto Nishikawa, Atsushi Kaida, Alejandro Parrales, Atul Ranjan, Mohamed A.A. Alalem, Hongyi Ren, Frank J. Schoenen, David K. Johnson, and Tomoo Iwakuma (Article)

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Sorafenib in Combination With Standard Chemotherapy for Children With High Allelic Ratio FLT3/ITD+ Acute Myeloid Leukemia: A Report From the Children's Oncology Group Protocol AAML1031, Jessica A. Pollard, Todd A. Alonzo, Robert Gerbing, Patrick Brown, Elizabeth Fox, John Choi, Brian Fisher, Betsy Hirsch, Samir Kahwash, Kelly Getz, John Levine, Lisa Eidenschink Brodersen, Michael R. Loken, Susana Raimondi, Katherine Tarlock, Andrew Wood, Lillian Sung, E Anders Kolb, Alan S. Gamis, Soheil Meshinchi, and Richard Aplenc (Article)

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Blood Count Recovery Following Induction Therapy for Acute Myeloid Leukemia in Children Does Not Predict Survival, Lauren Pommert, Todd M. Cooper, Robert B. Gerbing, Lisa Brodersen, Michael Loken, Alan S. Gamis, Richard Aplenc, Todd A. Alonzo, and Edwards Anders Kolb (Article)

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Next-Generation Sequencing of Minimal Residual Disease for Predicting Relapse after Tisagenlecleucel in Children and Young Adults with Acute Lymphoblastic Leukemia., Michael A. Pulsipher, Xia Han, Shannon L. Maude, Theodore W. Laetsch, Muna Qayed, Susana Rives, Michael W. Boyer, Hidefumi Hiramatsu, Gregory A. Yanik, Tim Driscoll, Douglas Myers, Peter Bader, Andre Baruchel, Jochen Buechner, Heather E. Stefanski, Creton Kalfoglou, Kevin Nguyen, Edward R. Waldron, Karen Thudium Mueller, Harald J. Maier, Gabor Kari, and Stephan A. Grupp (Article)

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Leukapheresis guidance and best practices for optimal chimeric antigen receptor T-cell manufacturing., Muna Qayed, Joseph P. McGuirk, Douglas Myers, Vinod Parameswaran, Edmund K. Waller, Peter Holman, Margarida Rodrigues, Lee F. Clough, and Jennifer Willert (Article)

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Hematopoietic Cell Transplantation for Congenital Dyserythropoietic Anemia: A Report from the Pediatric Transplant and Cellular Therapy Consortium., Hemalatha G. Rangarajan, Joseph R. Stanek, Hisham Abdel-Azim, Arunkumar Modi, Ann Haight, Christopher M. McKinney, Daniel J. McKeone, David K. Buchbinder, Emmanuel Katsanis, Ghada A. Abusin, Ibrahim A. Ahmed, Jason Law, Jorge Galvez Silva, Kanwaldeep K. Mallhi, Lauri M. Burroughs, Niketa Shah, Peter J. Shaw, Robert Greiner, Shalini Shenoy, Michael A. Pulsipher, and Rolla Abu-Arja (Article)

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Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Consortium Report., Liora M. Schultz, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Rayne H. Rouce, Vasant Chinnabhandar, Michael Kunicki, Valentin V. Barsan, A Yasemin Goksenin, Yimei Li, Sharon Mavroukakis, Emily Egeler, Kevin J. Curran, Crystal L. Mackall, and Theodore W. Laetsch (Article)

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Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine., Kallen Schwark, Dana Messinger, Jessica R. Cummings, Joshua Bradin, Abed Kawakibi, Clarissa M. Babila, Samantha Lyons, Sunjong Ji, Rodrigo T. Cartaxo, Seongbae Kong, Evan Cantor, Carl Koschmann, and Viveka Nand Yadav (Article)

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Adrenocortical Function in Children With Brain Tumors and Pediatric Hematopoietic Cell Transplantation Recipients., Koral Shah, Jennifer W. Boyd, Julia Broussard, Kevin Ginn, Rukhsana Rahmetulla, Kristy Hurst, and Rakesh K. Goyal (Article)

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Risk factors for hospital acquired venous thromboembolism in congenital heart disease patients: A report from the children's hospital acquired thrombosis (CHAT) consortium., Michael Silvey, Anh Thy H. Nguyen, Ernest K. Amankwah, Emily McElwaine, Brian Branchford, Amy Stillings, Emily Krava, Guy Young, Neil Goldenberg, and Julie Jaffray (Article)

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Ehrlichia-induced hemophagocytic lymphohistiocytosis in a pediatric kidney transplant recipient., Nisha S. Singh, Alexa L. Pagano, J Allyson Hays, Alexander Kats, Steven M. Dahl, Bradley A. Warady, Nathan T. Beins, and Dwight E. Yin (Article)

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Hematopoietic Cell Transplantation in the Treatment of Pediatric Acute Myelogenous Leukemia and Myelodysplastic Syndromes: Guidelines from the American Society of Transplantation and Cellular Therapy., Katherine Tarlock, Maria Luisa Sulis, Joseph H. Chewning, Jessica A. Pollard, Todd Cooper, Alan S. Gamis, Shalini Shenoy, Matthew Kutny, John Horan, Soheil Meshinchi, Jaap-Jan Boelens, Marie Bleakley, Paul A. Carpenter, and E Anders Kolb (Article)

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Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma., David T. Teachey, Meenakshi Devidas, Brent L. Wood, Zhiguo Chen, Robert J. Hayashi, Michelle L. Hermiston, Robert D. Annett, J Hunter Archer, Barbara L. Asselin, Keith August, Steve Y. Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok I. Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I. Patel, Eric S. Schafer, Tal Schechter, Neelam Singh, Amii C. Steele, Maria Luisa Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweidler-McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, and Elizabeth A. Raetz (Article)

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Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-κB subunit RelA., Anneke D. van Dijk, Fieke W. Hoff, Yihua Qiu, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Gaye N. Jenkins, Eveline S J M de Bont, Steven M. Kornblau, and Terzah M. Horton (Article)

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Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors., Laura van Iersel, Renee L. Mulder, Christian Denzer, Laurie E. Cohen, Helen A. Spoudeas, Lillian R. Meacham, Elaine Sugden, Antoinette Y N Schouten-van Meeteren, Eelco W. Hoving, Roger J. Packer, Gregory T. Armstrong, Sogol Mostoufi-Moab, Aline M. Stades, Dannis van Vuurden, Geert O. Janssens, Cécile Thomas-Teinturier, Robert D. Murray, Natascia Di Iorgi, Sebastian J C M M Neggers, Joel Thompson, Andrew A. Toogood, Helena Gleeson, Cecilia Follin, Edit Bardi, Lilibeth Torno, Briana Patterson, Vera Morsellino, Grit Sommer, Sarah C. Clement, Deokumar Srivastava, Cecilie E. Kiserud, Alberto Fernandez, Katrin Scheinemann, Sripriya Raman, Kevin C J Yuen, W Hamish Wallace, Louis S. Constine, Roderick Skinner, Melissa M. Hudson, Leontien C M Kremer, Wassim Chemaitilly, and Hanneke M. van Santen (Article)

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Practical considerations and consensus opinion for children's hospital-based inpatient hemostasis and thrombosis (HAT) consultative services: Communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis., Gary M. Woods, Leslie Raffini, Leonardo R. Brandão, Julie Jaffray, Brian R. Branchford, Christopher J. Ng, Sarah E. Sartain, Jennifer Pak, Christoph Male, Ayesha Zia, Mattia Rizzi, Nongnuch Sirachainan, Edward Vincent S. Faustino, Shannon L. Carpenter, and Neil A. Goldenberg (Article)

Works from 2021

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Next-Generation Sequencing in the Diagnosis of Rare Pediatric Sinonasal Tumors., Atif A. Ahmed, Divya Vundamati, Midhat Farooqi, Elena Repnikova, Timothy Zinkus, Maxine Hetherington, and Lorien Paulson (Article)

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MYOD1 as a prognostic indicator in rhabdomyosarcoma., Atif Ahmed, Sahibu Sultan M Habeebu, Midhat S. Farooqi, A S. Gamis, Elizabeth Gonzalez, Terrie Flatt, Ashley K. Sherman, Lea Surrey, Michael A. Arnold, Miriam Conces, Selene Koo, Nikolina Dioufa, Frederic G. Barr, and Maria G. Tsokos (Article)

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Subdural hemorrhage in a cohort with cerebral sinovenous thrombosis: Application to abusive head trauma., James Anderst, Shannon L. Carpenter, Terra N. Frazier, Brian Appavu, Michael Noetzel, Lauren A Beslow, Mukta Sharma, and International Pediatric Stroke Study Investigators (Article)

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Neighborhood poverty and pediatric allogeneic hematopoietic cell transplantation outcomes: a CIBMTR analysis., Kira Bona, Ruta Brazauskas, Naya He, Leslie Lehmann, Hisham Abdel-Azim, Ibrahim A. Ahmed, A Samer Al-Homsi, Mahmoud Aljurf, Staci D. Arnold, Sherif M. Badawy, Minoo Battiwalla, Sara Beattie, Neel S. Bhatt, Jignesh Dalal, Christopher E. Dandoy, Miguel Angel Diaz, Haydar A. Frangoul, César O. Freytes, Siddhartha Ganguly, Biju George, David Gomez-Almaguer, Theresa Hahn, Rammurti T. Kamble, Jennifer M. Knight, C Fred LeMaistre, Jason Law, Hillard M. Lazarus, Navneet S. Majhail, Richard F. Olsson, Jaime Preussler, Bipin N. Savani, Raquel Schears, Sachiko Seo, Akshay Sharma, Alok Srivastava, Amir Steinberg, David Szwajcer, Baldeep Wirk, Ayami Yoshimi, Nandita Khera, William A. Wood, Shahrukh Hashmi, Christine N. Duncan, and Wael Saber (Article)

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Comorbidities and complications in adults with pyruvate kinase deficiency., Audra N. Boscoe, Yan Yan, Elizabeth Hedgeman, Eduard J. van Beers, Hanny Al-Samkari, Wilma Barcellini, Stefan W. Eber, Bertil Glader, Hassan M. Yaish, Satheesh Chonat, Mukta Sharma, Kevin H M Kuo, Ellis J. Neufeld, Heng Wang, Madeleine Verhovsek, Sujit Sheth, and Rachael F. Grace (Article)

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Pyruvate kinase deficiency in children., Satheesh Chonat, Stefan W. Eber, Susanne Holzhauer, Nina Kollmar, D Holmes Morton, Bertil Glader, Ellis J. Neufeld, Hassan M. Yaish, Jennifer A. Rothman, Mukta Sharma, Yaddanapudi Ravindranath, Heng Wang, Vicky R. Breakey, Sujit Sheth, Heather A. Bradeen, Hasan Al-Sayegh, Wendy B. London, and Rachael F. Grace (Article)

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Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation., Thomas Cochran and Weijie Li (Article)

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Management of a hemispherotomy for Rasmussen encephalitis in a patient with mild factor 10 deficiency and low von Willebrand factor levels., Chandni Dargan, Christian Kaufman, Gabor Oroszi, Christopher P K Miller, Lucy Carter-Reardon, Eric Blue, and Brian M. Wicklund (Letter to the Editor)

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Outcomes of intensification of induction chemotherapy for children with high-risk acute myeloid leukemia: A report from the Children's Oncology Group., Caitlin W. Elgarten, Andrew C. Wood, Yimei Li, Todd A. Alonzo, Lisa Eidenschink Brodersen, Robert B. Gerbing, Kelly D. Getz, Y-S Vera Huang, Michael Loken, Soheil Meshinchi, Jessica A. Pollard, Lillian Sung, William G. Woods, E Anders Kolb, Alan S. Gamis, and Richard Aplenc (Article)

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Tisagenlecleucel infusion in patients with relapsed/refractory ALL and concurrent serious infection., Erin Hall, Dwight E. Yin, Rakesh K. Goyal, Atif Ahmed, Grace S. Mitchell, Shawn D. St Peter, Terrie Flatt, Ibrahim A. Ahmed, Weijie Li, Richard J. Hendrickson, Keith August, and Douglas Myers (Article)

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High-dose AraC is essential for the treatment of ML-DS independent of postinduction MRD: results of the COG AAML1531 trial., Johann Hitzler, Todd Alonzo, Robert Gerbing, Amy Beckman, Betsy Hirsch, Susana Raimondi, Karen Chisholm, Shelton Viola, Lisa Brodersen, Michael Loken, Spencer Tong, Todd Druley, Maureen O'Brien, Nobuko Hijiya, Amy Heerema-McKenney, Yi-Chang Wang, Reuven Shore, Jeffrey Taub, Alan S. Gamis, E Anders Kolb, and Jason N. Berman (Article)

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Heat shock factor 1 (HSF1-pSer326) predicts response to bortezomib-containing chemotherapy in pediatric AML: a COG report., Fieke W. Hoff, Anneke D. van Dijk, Yihua Qiu, Peter P. Ruvolo, Robert B. Gerbing, Amanda R. Leonti, Gaye N. Jenkins, A S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Eveline S J M de Bont, Sophia W M Bruggeman, Steven M. Kornblau, and Terzah M. Horton (Article)

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CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes., Benjamin J. Huang, Jenny L. Smith, Yi-Cheng Wang, Kassra Taghizadeh, Amanda R. Leonti, Rhonda E. Ries, Yanling Liu, Pandurang Kolekar, Katherine Tarlock, Robert Gerbing, Erin Crowgey, Scott N. Furlan, Timothy I. Shaw, Kohei Hagiwara, Lisa Wei, Todd M. Cooper, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Jason E. Farrar, Timothy Triche, Todd A. Alonzo, Xiaotu Ma, and Soheil Meshinchi (Article)

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A Prospective Observational Study of Antihemophilic Factor (Recombinant) Prophylaxis Related to Physical Activity Levels in Patients with Hemophilia A in the United States (SPACE)., Barbara A. Konkle, Doris V. Quon, Leslie Raffini, Michael Recht, Vlad C. Radulescu, Shannon L. Carpenter, Amy L. Dunn, Mei Lu, and Maureen Watt (Article)

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Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report., Patrick J. Leavey, Nadia N. Laack, Mark D. Krailo, Allen Buxton, R Lor Randall, Steven G. DuBois, Damon R. Reed, Holcombe E. Grier, Douglas S. Hawkins, Bruce Pawel, Helen Nadel, Richard B. Womer, G Douglas Letson, Mark Bernstein, Kenneth Brown, Alexis Maciej, Paul Chuba, Atif Ahmed, Daniel J. Indelicato, Dian Wang, Neyssa Marina, Richard Gorlick, Katherine A. Janeway, and Leo Mascarenhas (Article)

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Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia., John E. Levine, Stephan A. Grupp, Michael A. Pulsipher, Andrew C. Dietz, Susana Rives, Douglas Myers, Keith August, Michael R. Verneris, Jochen Buechner, Theodore W. Laetsch, Henrique Bittencourt, Andre Baruchel, Michael W. Boyer, Barbara De Moerloose, Muna Qayed, Stella M. Davies, Christine L. Phillips, Timothy A. Driscoll, Peter Bader, Krysta Schlis, Patricia A. Wood, Rajen Mody, Lan Yi, Mimi Leung, Lamis K. Eldjerou, Carl H. June, and Shannon L. Maude (Article)

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A Person-Centered Approach to Symptom Assessment and Management for Children and Adolescents Receiving Cancer Treatment., Lauri A. Linder, Suzanne Ameringer, Kristin Stegenga, Catherine Fiona Macpherson, and Jeanne Erickson (Article)

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Feasibility and acceptability of a game-based symptom-reporting app for children with cancer: perspectives of children and parents., Lauri A. Linder, Amy R. Newman, Kristin Stegenga, Yin-Shun Chiu, Sarah E. Wawrzynski, Heidi Kramer, Charlene Weir, Scott Narus, and Roger Altizer (Article)

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T-lymphoblastic leukemia/lymphoma with interfollicular growth pattern and Castleman-like morphologic features, Weijie Li, Alexander Kats, Linda D. Cooley, Midhat Farooqi, and Keith August (Article)

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Generalized eczematous dermatitis and pruritus responsive to dupilumab in a patient with immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome., Maeve C. Maher, Erin Hall, and Kimberly A. Horii (Article)

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Polycythemia vera in a 2-year-old child with a JAK2 exon 12 deletion., Sarah E. Mc Dermott, Nicole Kucine, Midhat S. Farooqi, Weijie Li, and Michael Silvey (Letter to the Editor)

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Perspectives on outpatient administration of CAR-T cell therapy in aggressive B-cell lymphoma and acute lymphoblastic leukemia., Douglas Myers, Michael R. Verneris, Andre Goy, and Richard T. Maziarz (Article)

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Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia., P Narayanan, T-K Man, R B Gerbing, R Ries, A M Stevens, Y-C Wang, X Long, A S. Gamis, T Cooper, S Meshinchi, T A Alonzo, and M S Redell (Article)

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Results of a phase 2, multicenter, single-arm, open-label study of lenalidomide in pediatric patients with relapsed or refractory acute myeloid leukemia., Maureen M. O'Brien, Todd A. Alonzo, Todd M. Cooper, John E. Levine, Patrick A. Brown, Tamra Slone, Keith August, Bouchra Benettaib, Noha Biserna, Jennifer Poon, Meera Patturajan, Nianhang Chen, Mathew Simcock, Linda Zimmerman, and E Anders Kolb (Article)

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Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531, Jessica A. Pollard, Erin M. Guest, Todd A. Alonzo, Robert B. Gerbing, Mike R. Loken, Lisa Eidenschink Brodersen, E Anders Kolb, Richard Aplenc, Soheil Meshinchi, Susana C. Raimondi, Betsy Hirsch, and Alan S. Gamis (Article)

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Novel prenatal diagnosis of protein C deficiency and primary prophylaxis with protein C concentrate., Alexandra Prosser, Lauren Amos MD, and Mukta Sharma (Article)

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Salmon-colored granules in the leukemic blasts of B-lymphoblastic leukemia with iAMP21., Alexandra Prosser and Weijie Li (Article)

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Anaplastic Lymphoma Kinase Inhibitor in Treatment of Inflammatory Myofibroblastic Tumor of the Tongue in Infancy., Karishma Rao, Sana Farooki, Erin M. Guest, Katherine Chastain, Melissa Gener, and Gangaram Akangire (Article)

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Survival Following Relapse in Children with Acute Myeloid Leukemia: A Report from AML-BFM and COG., Mareike Rasche, Martin Zimmermann, Emma Steidel, Todd Alonzo, Richard Aplenc, Jean-Pierre Bourquin, Heidrun Boztug, Todd Cooper, A S. Gamis, Robert B. Gerbing, Iveta Janotova, Jan-Henning Klusmann, Thomas Lehrnbecher, Nora Mühlegger, Nils V. Neuhoff, Naghmeh Niktoreh, Lucie Sramkova, Jan Stary, Katharina Waack, Christiane Walter, Ursula Creutzig, Michael Dworzak, Gertjan Kaspers, Edward Anders Kolb, and Dirk Reinhardt (Article)

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Out-of-specification tisagenlecleucel does not compromise safety or efficacy in pediatric acute lymphoblastic leukemia., Jenna Rossoff, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine L. Phillips, Heather Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Douglas Myers, Nicole Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Michael Kunicki, Vasant Chinnabhandar, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, and Liora M. Schultz (Article)

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Malignant Granular Cell Tumor of the Lower Extremity in an Adolescent Male., Karina Shah, Joy M. Fulbright, Alexander Katz, Lei Zhang, Dale E. Jarka, and Michael Lypka (Article)

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Outcomes of pediatric patients with therapy-related myeloid neoplasms., Akshay Sharma, Sujuan Huang, Ying Li, Russell J. Brooke, Ibrahim A. Ahmed, Heather B. Allewelt, Persis Amrolia, Alice Bertaina, Neel S. Bhatt, Marc B. Bierings, Joshua Bies, Claire Brisset, Jennifer E. Brondon, Ann Dahlberg, Jean-Hugues Dalle, Hesham Eissa, Mony Fahd, Adam Gassas, Nicholas J. Gloude, W Scott Goebel, Erika S. Goeckerman, Katherine Harris, Richard Ho, Michelle P Hudspeth, Jeffrey S. Huo, David Jacobsohn, Kimberly A. Kasow, Emmanuel Katsanis, Saara Kaviany, Amy K. Keating, Nancy A. Kernan, Yiouli P. Ktena, Colette R. Lauhan, Gerardo López-Hernandez, Paul L. Martin, Kasiani C. Myers, Swati Naik, Alberto Olaya-Vargas, Toshihiro Onishi, Mohamed Radhi, Shanti Ramachandran, Kristie Ramos, Hemalatha G. Rangarajan, Philip A. Roehrs, Megan E. Sampson, Peter J. Shaw, Jodi L. Skiles, Katherine Somers, Heather J. Symons, Marie de Tersant, Allison N. Uber, Birgitta Versluys, Cheng Cheng, and Brandon M. Triplett (Article)

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CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group., Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda Leonti, Jenny L. Smith, Tiffany A. Hylkema, William G. Woods, Todd M. Cooper, E Anders Kolb, A S. Gamis, Richard Aplenc, Todd A. Alonzo, and Soheil Meshinchi (Article)

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A review on clotting disorders and retinal hemorrhages: Can they mimic abuse?, Avrey Thau, Brooke Saffren, James Anderst, Shannon L. Carpenter, and Alex V. Levin (Article)

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Retinal hemorrhage and bleeding disorders in children: A review., Avrey Thau, Brooke Saffren, Helena Zakrzewski, James Anderst, Shannon L. Carpenter, and Alex Levin (Article)

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Musculoskeletal impairments in children receiving intensive therapy for acute leukemia or undergoing hematopoietic stem cell transplant: A report from the Children's Oncology Group., Joel Thompson, Brian Fisher, Lillian Sung, Christopher Dvorak, Ha Dang, Tammy Lo, and Sarah Alexander (Article)

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Tisagenlecleucel immunogenicity in relapsed/refractory acute lymphoblastic leukemia and diffuse large B-cell lymphoma., Karen Thudium Mueller, Stephan A. Grupp, Shannon L. Maude, John E. Levine, Michael A. Pulsipher, Michael W. Boyer, Keith August, Douglas Myers, Constantine S. Tam, Ulrich Jaeger, Stephen Ronan Foley, Peter Borchmann, Stephen J. Schuster, Edmund K. Waller, Rakesh Awasthi, Bernd Potthoff, Andy Warren, Edward R. Waldron, Fraser McBlane, Andrea Chassot-Agostinho, and Theodore W. Laetsch (Article)

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momHealth: A Feasibility Study of a Multibehavioral Health Intervention for Pregnant and Parenting Adolescent Mothers., Karen A. Wambach, Ann M. Davis, Eve Lynn Nelson, Kelli Snow, Annie Yungmeyer, Rachel Muzzy, Karman Romero, and Megan Murray (Article)

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Aligning EHR Data for Pediatric Leukemia With Standard Protocol Therapy., Nicole Wood, Sierra Davis, Karen Lewing, Janelle R. Noel-Macdonnell PhD, Earl F. Glynn, Doina Caragea, and Mark A. Hoffman (Article)

Works from 2020

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Characterization of the severe phenotype of pyruvate kinase deficiency., Hanny Al-Samkari, Eduard J. van Beers, D Holmes Morton, Wilma Barcellini, Stefan W. Eber, Bertil Glader, Hassan M. Yaish, Satheesh Chonat, Kevin H M Kuo, Nina Kollmar, Jenny M. Despotovic, Dagmar Pospíšilová, Christine M. Knoll, Janet L. Kwiatkowski, Yves D Pastore, Alexis A. Thompson, Marcin W. Wlodarski, Yaddanapudi Ravindranath, Jennifer A. Rothman, Heng Wang, Susanne Holzhauer, Vicky R. Breakey, Madeleine M. Verhovsek, Joachim Kunz, Sujit Sheth, Mukta Sharma, Melissa J. Rose, Heather A. Bradeen, Melissa N. McNaull, Kathryn Addonizio, Hasan Al-Sayegh, Wendy B. London, and Rachael F. Grace (Letter to the Editor)

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The Need for Comprehensive Care for Persons with Chronic Immune Thrombocytopenic Purpura., Kristin T. Ansteatt, Chanel J. Unzicker, Marsha L. Hurn, Oluwaseun O. Olaiya, Diane J. Nugent, and Michael D. Tarantino (Article)

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Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children's Oncology Group., Richard Aplenc, Soheil Meshinchi, Lillian Sung, Todd Alonzo, John Choi, Brian Fisher, Robert Gerbing, Betsy Hirsch, Terzah Horton, Samir Kahwash, John Levine, Michael Loken, Lisa Brodersen, Jessica Pollard, Susana Raimondi, Edward Anders Kolb, and A S. Gamis (Article)

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Desensitization to pegaspargase in children with acute lymphoblastic leukemia and lymphoblastic lymphoma., Keith J. August, Sana Farooki, Joy M. Fulbright, Amanda August, Jay M. Portnoy, Lauren Pommert, Michael J. Burke, and Erin M. Guest (Article)

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Treatment of children with relapsed and refractory acute lymphoblastic leukemia with mitoxantrone, vincristine, pegaspargase, dexamethasone, and bortezomib., Keith J. August, Erin M. Guest, Karen Lewing, J Allyson Hays, and A S. Gamis (Article)