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Works from 2024

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Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial., Giselle L Saulnier Sholler, Genevieve Bergendahl, Elizabeth C. Lewis, Jacqueline Kraveka, William Ferguson, Abhinav B. Nagulapally, Karl Dykema, Valerie I Brown, Michael S. Isakoff, Joseph Junewick, Deanna Mitchell, Jawhar Rawwas, William Roberts, Don Eslin, Javier Oesterheld, Randal K. Wada, Devang Pastakia, Virginia Harrod, Kevin Ginn, Raya Saab, Kevin Bielamowicz, Jason Glover, Eugenia Chang, Gina K. Hanna, Daniel Enriquez, Tyler Izatt, Rebecca F Halperin, Abigail Moore, Sara A. Byron, William P D Hendricks, and Jeffrey M. Trent (Article)

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Therapeutic potential of combating cancer by restoring wild-type p53 through mRNA nanodelivery., Divya Kamath, Tomoo Iwakuma, and Stefan H. Bossmann (Article)

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Family Rules and Routines During the Early Phases of Pediatric Cancer Treatment: Associations With Child Emotional and Behavioral Health., Carolyn R. Bates, Vincent S. Staggs, Kelsey Dean, Keith August, Christie A. Befort, Lynne Covitz, and Meredith Dreyer (Article)

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A road map for the treatment of pediatric diffuse midline glioma., Carl Koschmann, Wajd N. Al-Holou, Marta M. Alonso, Jamie Anastas, Pratiti Bandopadhayay, Tara Barron, Oren Becher, Rodrigo Cartaxo, Maria G. Castro, Chan Chung, Madison Clausen, Derek Dang, Robert Doherty, Ryan Duchatel, Matthew Dun, Mariella Filbin, Andrea Franson, Stefanie Galban, Marc Garcia Moure, Hugh Garton, Pruthvi Gowda, Joana Graca Marques, Cynthia Hawkins, Allison Heath, Esther Hulleman, Sunjong Ji, Chris Jones, Lindsay Kilburn, Cassie Kline, Michael A. Koldobskiy, Daniel Lim, Pedro R. Lowenstein, Q Richard Lu, Joanna Lum, Stephen Mack, Suresh Magge, Bernard Marini, Donna Martin, Neena Marupudi, Dana Messinger, Rajen Mody, Meredith Morgan, Mateus Mota, Karin Muraszko, Sabine Mueller, Siva Kumar Natarajan, Javad Nazarian, Michael Niculcea, Nicholas Nuechterlein, Hideho Okada, Valerie Opipari, Manjunath P. Pai, Sharmistha Pal, Erik Peterson, Timothy Phoenix, John R. Prensner, Matthew Pun, G Praveen Raju, Zachary J. Reitman, Adam Resnick, David Rogawski, Amanda Saratsis, Stefanie G. Sbergio, Mark Souweidane, James M. Stafford, Theophilos Tzaridis, Sujatha Venkataraman, Orazio Vittorio, Jack Wadden, Daniel Wahl, Robert J. Wechsler-Reya, Viveka Nand Yadav, Xu Zhang, Qiang Zhang, and Sriram Venneti (Article)

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A comprehensive analysis of neuroblastoma incidence, survival, and racial and ethnic disparities from 2001 to 2019., Kevin Campbell, David A. Siegel, Puja J. Umaretiya, Shifan Dai, Andras Heczey, Philip J. Lupo, Jeremy M. Schraw, Trevor D. Thompson, Michael E. Scheurer, and Jennifer H. Foster (Article)

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A modified nucleoside O6-methyl-2'-deoxyguanosine-5'-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner., Zi-Hui Wang, Jin Li, Qian Liu, Jian-Chang Qian, Qing-Qing Li, Qing-Yu Wang, Lv-Tao Zeng, Si-Jia Li, Xin Gao, Jia-Xin Pan, Xu-Fan Gao, Kun Wu, Guo-Xin Hu, Tomoo Iwakuma, and Jian-Ping Cai (Article)

Works from 2023

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Lessons learnt in the first year of an Australian pediatric cardio oncology clinic., Claudia Toro, Ben Felmingham, Mangesh Jhadav, David S. Celermajer, Andre La Gerche, John O'Sullivan, Sanjeev Kumar, Marion K. Mateos, Joy M. Fulbright, Dinisha Govender, Lane Collier, Michael Cheung, David D. Eisenstat, Peter W. Lange, Julian Ayer, David A. Elliott, and Rachel Conyers (Article)

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Colonic L-cell impairment in aged subjects with type 2 diabetes leads to diminished GLP-1 production., Qing-Yu Wang, Wei Zhang, Yue Zhao, Hui-Lian Chen, Qian Liu, Zi-Hui Wang, Lv-Tao Zeng, Jin Li, Si-Jie Chen, Lei Wei, Tomoo Iwakuma, and Jian-Ping Cai (Article)

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Mediators and Moderators of Active Music Engagement to Reduce Traumatic Stress Symptoms and Improve Well-being in Parents of Young Children With Cancer., Sheri L. Robb, Kristin Stegenga, Susan M. Perkins, Timothy E. Stump, Karen M. Moody, Amanda K. Henley, Jessica MacLean, Seethal A. Jacob, David Delgado, and Paul R. Haut (Article)

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Rare Tumors: Opportunities and challenges from the Children's Oncology Group perspective., Kris Ann P. Schultz, Murali Chintagumpala, Jin Piao, Kenneth S. Chen, Rachana Shah, Robyn D. Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L. Berry, Allison F. O'Neill, Lauren M. Vasta, Ashley Flynn, Sarah G. Mitchell, Brittani Kn Seynnaeve, Jeremy Rosenblum, Samara L. Potter, Junne Kamihara, Carlos Rodriguez-Galindo, Douglas S. Hawkins, and Theodore W. Laetsch (Article)

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Trends in dedicated care for females with bleeding disorders within U.S. hemophilia treatment centers., Allison P. Wheeler, Ming Y. Lim, Patricia S. Huguelet, Julie Jaffray, Janice M. Staber, Kerry Funkhouser, Shannon L. Carpenter, and Angela C. Weyand (Letter to the Editor)

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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory., Iker Ausejo-Mauleon, Sara Labiano, Daniel de la Nava, Virginia Laspidea, Marta Zalacain, Lucía Marrodán, Marc García-Moure, Marisol González-Huarriz, Irati Hervás-Corpión, Laasya Dhandapani, Silvestre Vicent, Maria Collantes, Iván Peñuelas, Oren J. Becher, Mariella G. Filbin, Li Jiang, Jenna Labelle, Carlos A O de Biagi-Junior, Javad Nazarian, Sandra Laternser, Timothy N. Phoenix, Jasper van der Lugt, Mariette Kranendonk, Raoull Hoogendijk, Sabine Mueller, Carlos De Andrea, Ana C. Anderson, Elizabeth Guruceaga, Carl Koschmann, Viveka Nand Yadav, Jaime Gállego Pérez-Larraya, Ana Patiño-García, Fernando Pastor, and Marta M. Alonso (Article)

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Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways., Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M. Waszak, Stefan R. Sweha, Mateus Mota, Matthew Pun, Akash Deogharkar, Chan Chung, Rohinton S. Tarapore, Samuel Ramage, Andrew Chi, Patrick Y. Wen, Isabel Arrillaga-Romany, Tracy T. Batchelor, Nicholas A. Butowski, Ashley Sumrall, Nicole Shonka, Rebecca A. Harrison, John de Groot, Minesh Mehta, Matthew D. Hall, Doured Daghistani, Timothy F. Cloughesy, Benjamin M. Ellingson, Kevin Beccaria, Pascale Varlet, Michelle M. Kim, Yoshie Umemura, Hugh Garton, Andrea Franson, Jonathan Schwartz, Rajan Jain, Maureen Kachman, Heidi Baum, Charles F. Burant, Sophie L. Mottl, Rodrigo T. Cartaxo, Vishal John, Dana Messinger, Tingting Qin, Erik Peterson, Peter Sajjakulnukit, Karthik Ravi, Alyssa Waugh, Dustin Walling, Yujie Ding, Ziyun Xia, Anna Schwendeman, Debra Hawes, Fusheng Yang, Alexander R. Judkins, Daniel Wahl, Costas A. Lyssiotis, Daniel de la Nava, Marta M. Alonso, Augustine Eze, Jasper Spitzer, Susanne V. Schmidt, Ryan J. Duchatel, Matthew D. Dun, Jason E. Cain, Li Jiang, Sylwia A. Stopka, Gerard Baquer, Michael S. Regan, Mariella G. Filbin, Nathalie Y R Agar, Lili Zhao, Chandan Kumar-Sinha, Rajen Mody, Arul Chinnaiyan, Ryo Kurokawa, Drew Pratt, Viveka Nand Yadav, Jacques Grill, Cassie Kline, Sabine Mueller, Adam Resnick, Javad Nazarian, Joshua E. Allen, Yazmin Odia, Sharon L. Gardner, and Carl Koschmann (Article)

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Long-term follow-up of patients with congenital thrombotic thrombocytopenia purpura receiving a plasma-derived factor VIII (Koate) that contains ADAMTS13., Tammuella Chrisentery-Singleton, Lisa N. Boggio, Manuel D. Carcao, Sami Ibrahimi, Osman Khan, Arash Mahajerin, Anita Rajasekhar, Vivek Sharma, MacGregor Steele, Marcela Torres, Frank J. Rodino, and Shannon L. Carpenter (Article)

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ROS1 Alterations as a Potential Driver of Gliomas in Infant, Pediatric, and Adult Patients., David M. Meredith, Linda D. Cooley, Adrian Dubuc, Jennifer Morrissette, Robyn T. Sussman, MacLean P. Nasrallah, Pamela Rathbun, Kai Lee Yap, Nitin Wadhwani, Liming Bao, Daynna J. Wolff, Cristiane Ida, Madina Sukhanova, Craig Horbinski, Lawrence J. Jennings, Midhat S. Farooqi, Melissa Gener, Kevin Ginn, Kwok Ling Kam, Koji Sasaki, Rashmi Kanagal-Shamanna, Sanda Alexandrescu, Daniel Brat, and Xinyan Lu (Article)

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Tisagenlecleucel utilisation and outcomes across refractory, first relapse and multiply relapsed B-cell acute lymphoblastic leukemia: a retrospective analysis of real-world patterns., Valentin Barsan, Yimei Li, Snehit Prabhu, Christina Baggott, Khanh Nguyen, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy Moskop, Susanne Baumeister, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Stacy Cooper, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy Keating, Vanessa Fabrizio, Vasant Chinnabhandar, Michael Kunicki, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, and Liora M. Schultz (Article)

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Valosin-containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: A report from the Children's Oncology Group., Fieke W. Hoff, Yihua Qiu, Brandon D. Brown, Robert B. Gerbing, Amanda R. Leonti, Rhonda E. Ries, Alan S. Gamis, Richard Aplenc, Edward Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Gaye N. Jenkins, Terzah M. Horton, and Steven M. Kornblau (Article)

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Mediport use as an acceptable standard for CAR T cell infusion., Maya Eylon, Snehit Prabhu, Samuel John, Maxwell J M King, Dhruv Bhatt, Kevin J. Curran, Courtney Erickson, Nicole A. Karras, Christine L. Phillips, Prakash Satwani, Michelle Hermiston, Erica Southworth, Susanne H C Baumeister, Julie-An Talano, Margaret L. MacMillan, Jenna Rossoff, Challice L. Bonifant, Douglas Myers, Rayne H. Rouce, Keri Toner, Timothy A. Driscoll, Emmanuel Katsanis, Dana B. Salzberg, Deborah Schiff, Satiro N. De Oliveira, Christian M. Capitini, Holly L. Pacenta, Thomas Pfeiffer, Niketa C. Shah, Van Huynh, Jodi L. Skiles, Ellen Fraint, Kevin O. McNerney, Troy C. Quigg, Joerg Krueger, John A. Ligon, Vanessa A. Fabrizio, Christina Baggott, Theodore W. Laetsch, and Liora M. Schultz (Article)

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Editorial: Stem cells and the immune system., John M. Perry and Meng Zhao (Editorial)

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Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis., Sara Zarnegar-Lumley, Todd A. Alonzo, Robert B. Gerbing, Megan Othus, Zhuoxin Sun, Rhonda E. Ries, Jim Wang, Amanda Leonti, Matthew A. Kutny, Fabiana Ostronoff, Jerald P. Radich, Frederick R. Appelbaum, Era L. Pogosova-Agadjanyan, Kristen O'Dwyer, Martin S. Tallman, Mark Litzow, Ehab Atallah, Todd M. Cooper, Richard A. Aplenc, Omar Abdel-Wahab, Alan S. Gamis, Selina Luger, Harry Erba, Ross Levine, E Anders Kolb, Derek L. Stirewalt, Soheil Meshinchi, and Katherine Tarlock (Article)

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Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma., Soumya M. Turaga, Vikalp Vishwakarma, Stacey L. Hembruff, Benjamin K. Gibbs, Priya Sabu, Rajni V. Puri, Harsh B. Pathak, Glenson Samuel, and Andrew K. Godwin (Article)

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Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development, Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, and Bin Zhou (Article)

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Characterization of an Mtbp Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model, Atul Ranjan, Elizabeth A. Thoenen, Atsushi Kaida, Stephanie Wood, Terry Van Dyke, and Tomoo Iwakuma (Article)

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A Genomics Driven Pluripotent Stem Cell Model of Infant Acute Lymphoblastic Leukemia, Meagan Vacek, Jacqelyn Nemechek, Julia Draper, Irina Pushel, Bradley Thornton, Molly Leyda, Priyanka Prem Kumar, Midhat S. Farooqi, Jay L. Vivian, Erin M. Guest, and John M. Perry (Poster)

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A phase II trial of nifurtimox combined with topotecan and cyclophosphamide for refractory or relapsed neuroblastoma and medulloblastoma., Don Eslin, Peter E Zage, Genevieve Bergendahl, Elizabeth Lewis, William Roberts, Jacqueline Kraveka, Deanna Mitchell, Michael S. Isakoff, Jawhar Rawwas, Randal K. Wada, Mark Fluchel, Valerie I. Brown, Kevin Ginn, Timothy Higgins, Abhinav BeeravallyNagulapally, Karl Dykema, Gina Hanna, William Ferguson, and Giselle L. Saulnier Sholler (Article)

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CD19-negative B-cell precursors in bone marrow: A potential mimicker for CD19-negative B-lymphoblastic leukemia by flow cytometry in patients with anti-CD19 treatment., Weijie Li, Ruth Morgan, Roxanne Nieder, Sahibu Sultan M Habeebu, and Douglas Myers (Article)

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Evaluation of venous thromboembolism risk factors reveals subtype heterogenicity in children with central venous catheters: a multicenter study from the Children's Hospital Acquired Thrombosis consortium., Julie Jaffray, Maua Mosha, Brian Branchford, Neil A. Goldenberg, Michael Silvey, Stacy E. Croteau, John H. Fargo, James D. Cooper, Nihal Bakeer, Amy Stillings, Emily Krava, Guy Young, and Ernest K. Amankwah (Article)

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Minimal residual disease predicts outcomes in KMT2A-rearranged but not KMT2A-germline infant acute lymphoblastic leukemia: Report from Children's Oncology Group study AALL0631., Kelly E. Faulk, John A. Kairalla, ZoAnn E. Dreyer, Andrew J. Carroll, Nyla A. Heerema, Meenakshi Devidas, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Michael Borowitz, Cindy Wang, Erin M. Guest, and Patrick A. Brown (Article)

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Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia, Eline J M Bertrums, Jenny L. Smith, Lauren Harmon, Rhonda E. Ries, Yi-Cheng J. Wang, Todd A. Alonzo, Andrew J. Menssen, Karen M. Chisholm, Amanda R. Leonti, Katherine Tarlock, Fabiana Ostronoff, Era L. Pogosova-Agadjanyan, Gertjan J L Kaspers, Henrik Hasle, Michael Dworzak, Christiane Walter, Nora Muhlegger, Cristina Morerio, Laura Pardo, Betsy Hirsch, Susana Raimondi, Todd M. Cooper, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Jason E. Farrar, Derek Stirewalt, Xiaotu Ma, Tim I. Shaw, Scott N. Furlan, Lisa Eidenschink Brodersen, Michael R. Loken, Marry M. Van den Heuvel-Eibrink, C Michel Zwaan, Timothy J. Triche, Bianca F. Goemans, and Soheil Meshinchi (Article)

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SARS-CoV-2 infections in patients enrolled on the Children's Oncology Group standard-risk B-cell acute lymphoblastic leukemia trial, AALL1731., Caitlin W. Elgarten, John A. Kairalla, Joel Thompson, Tamara P. Miller, Cindy Wang, Susan Conway, Mignon L. Loh, Elizabeth A. Raetz, Sumit Gupta, Rachel E. Rau, Anne Angiolillo, Karen R. Rabin, and Sarah Alexander (Article)

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Management and outcomes in secondary diabetes among pediatric patients hospitalized with hemophagocytic lymphohistiocytosis., Cintya Schweisberger, Nila Palaniappan, Nicole Wood, Lauren Amos MD, and Kelsee Halpin (Article)

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Humoral and cellular response to the COVID-19 vaccine in immunocompromised children., Heather A. Morgans, Todd Bradley, Linda Flebbe-Rehwaldt, Rangaraj Selvarangan, Amber Bagherian, Aliessa P. Barnes, Julie A. Bass, Ashley M. Cooper, Ryan T. Fischer, Steve Kleiboeker, Brian R. Lee, Cas LeMaster, Kelsey Markus, Stephen Morrison, Angela Myers, Douglas Myers, Erin Payne, Jennifer E. Schuster, Sarah Standley, Andrea B. Wieser, and Bradley A. Warady (Article)

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HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL., Kevin O. McNerney, Stephanie J. Si Lim, Kyle Ishikawa, Alexandra Dreyzin, Anant Vatsayan, John J. Chen, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine Philips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Michael Verneris, Douglas Myers, Nicole A. Karras, Patrick Brown, Challice L. Bonifant, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Susanne H C Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, and Liora M. Schultz (Article)

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Prevalence of Iron Deficiency in Patients with Inherited Bleeding Disorders, Thomas Cochran, Brian R. Lee, and Shannon L. Carpenter (Poster)

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Real-Time Quantitative Measurement of Tumor Cell Migration and Invasion Following Synthetic mRNA Transfection., Taeju Park and Neka Large (Article)

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Editorial: Genetic and epigenetic regulation of stem cells by the immune system in homeostasis, regeneration, and oncogenesis., John M. Perry and Pengxu Qian (Editorial)

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Switching from Sucrose-Formulated rFVIII to Octocog Alfa (BAY 81-8973) Prophylaxis Improves Bleed Outcomes in the LEOPOLD Clinical Trials., Gili Kenet, Thomas Moulton, Brian M. Wicklund, Sanjay P. Ahuja, Miguel Escobar, and Johnny Mahlangu (Article)

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Integrated genetic profiling of archival pediatric high-grade glial tumors and reassessment with 2021 WHO classification of paediatric CNS tumours, Linda D. Cooley, Lisa A. Lansdon, Kris Laurence, John Herriges, Lei Zhang, Elena Repnikova, Julie M. Joyce, Preeti Thakor, Lisa Warren, Scott C. Smith, Byunggil Yoo, Melissa Gener, Kevin Ginn, and Midhat S. Farooqi (Article)

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Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia., Jason E. Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda Ries, Tiffany Hylkema, Era L. Pogosova-Agadjanyan, Sneha Challa, Amanda Leonti, Timothy I. Shaw, Timothy J. Triche, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Xiaotu Ma, Derek L. Stirewalt, Todd A. Alonzo, and Soheil Meshinchi (Article)

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Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group, Romy E. van Weelderen, Kim Klein, Christine J. Harrison, Yilin Jiang, Jonas Abrahamsson, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Barbara Buldini, Barbara De Moerloose, Michael N. Dworzak, Sarah Elitzur, José M. Fernández Navarro, Robert B. Gerbing, Bianca F. Goemans, Hester A. de Groot-Kruseman, Erin M. Guest, Shau-Yin Ha, Henrik Hasle, Charikleia Kelaidi, Hélène Lapillonne, Guy Leverger, Franco Locatelli, Riccardo Masetti, Takako Miyamura, Ulrika Norén-Nyström, Sophia Polychronopoulou, Mareike Rasche, Jeffrey E. Rubnitz, Jan Stary, Anne Tierens, Daisuke Tomizawa, C Michel Zwaan, and Gertjan J L Kaspers (Article)

A genomics driven pluripotent stem cell model of infant acute lymphoblastic leukemia, Jacqelyn Nemechek, Julia Draper, Sarah McDermott, Irina Pushel, Midhat S. Farooqi, Erin M. Guest, John M. Perry, and Jay L. Vivian

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A Pediatric Case of Treatment-related Myelodysplastic Syndrome While on Therapy for Pre-B Acute Lymphoblastic Leukemia., Sara McElroy, Douglas Myers, and Terrie Flatt (Article)

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A Pilot Study of Azacitidine as Epigenetic Priming for Chemotherapy in Infants Less Than 1 Year of Age with KMT2A-Rearranged Acute Lymphoblastic Leukemia (ALL); Results from the Children’s Oncology Group (COG) Trial AALL15P1, Erin M. Guest, John Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew Carroll, Nyla A. Heerema, Holly Kubaney, Amanda August, Melinda Pauly, Daniel Wechsler, Rodney Miles, Joel Reid, Cynthia Kihei, Lia Gore, Elizabeth Raetz, Stephen Hunger, Mignon Loh, and Patrick Brown

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Bone Marrow Transplant For Macrophage Activation Syndrome In Systemic Juvenile Idiopathic Arthritis​, Shailly Gaur, Michael J. Holland, J Allyson Hays, and Ibrahim A. Ahmed (Poster)

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Interaction between Crk and β-III spectrin during brain development and neurodegeneration, Shufei Zhuang, Jay L. Vivian, David K. Johnson, Lance Rodan, Tom Curran, and Taeju Park

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Macrophage Mediated Cancer Cell Targeting, Molly Leyda, Jacqelyn Nemechek, John Szarejko, John M. Perry, and Douglas Myers

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Overexpression of Crk and CrkL Increases the Motility of High-Grade Glioma Cells, Neka Large and Taeju Park

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p53 genetic sensor system to identify novel mutant p53 reactivators, Mrinalini Bhosale, Alejandro Parrales, Mohamed A.A. Alalem, Atul Ranjan, Elizabeth Thoenen, and Tomoo Iwakuma

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Pathologic, cytogenetic, and molecular features of acute myeloid leukemia with megakaryocytic differentiation: A report from the Children's Oncology Group., Karen M. Chisholm, Jenny Smith, Amy E. Heerema-McKenney, John K. Choi, Rhonda E. Ries, Betsy A. Hirsch, Susana C. Raimondi, Yi-Cheng Wang, Alice Dang, Todd A. Alonzo, Lillian Sung, Richard Aplenc, Alan S. Gamis, Soheil Meshinchi, and Samir B. Kahwash (Article)

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Skin Toxicity Due to Mercaptopurine in Maintenance Therapy Among Children With Acute Lymphoblastic Leukemia., Kayeleigh Higgerson and Terrie Flatt (Article)

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Stem Like T Cells in Anti-cancer Immunosurveillance Against Therapy-resistant Pediatric Cancer, Fang Tao, Sara McElroy, Jacqelyn Nemechek, Irina Pushel, Santosh Khanal, John Szarejko, Todd Bradley, Douglas Myers, and John M. Perry

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Therapeutic targeting of prenatal pontine ID1 signaling in DMG, Dana Messinger, Garrett Gibson, Micah K. Harris, Jessica R. Cummings, Chase Thomas, Tao Yang, Stefan R. Sweha, Rinette Woo, Robert Siddaway, Martin Burkert, Stefanie Stallard, Tingting Qin, Brendan Mullan, Ruby Siada, Ramya Ravindran, Michael Niculcea, Abigail Dowling, Joshua Bradin, Kevin F. Ginn, Melissa A H Gener, Kathleen Dorris, Nicholas A. Vitanza, Susanne V. Schmidt, Cynthia Hawkins, Sebastian M. Waszak, Sriram Venneti, and Viveka Nand Yadav

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Identification of small extracellular vesicle protein biomarkers for pediatric Ewing Sarcoma., Soumya M. Turaga, Mihaela E. Sardiu, Vikalp Vishwakarma, Amrita Mitra, Leonidas E. Bantis, Rashna Madan, Michael L. Merchant, Jon B. Klein, Glenson Samuel, and Andrew K. Godwin (Article)

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Perinucleolar Compartment (PNC) Prevalence as an Independent Prognostic Factor in Pediatric Ewing Sarcoma: A Multi-Institutional Study., Elizabeth Gonzalez, Atif A. Ahmed, Laura McCarthy, Katherine Chastain, Sahibu Sultan M Habeebu, Marta Zapata-Tarres, Rocio Cardenas-Cardos, Liliana Velasco-Hidalgo, Celso Corcuera-Delgado, Rodolfo Rodriguez-Jurado, Lilia García-Rodríguez, Alejandro Parrales, Tomoo Iwakuma, Midhat S. Farooqi, Brian R. Lee, Scott J. Weir, and Terrie Flatt (Article)

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More than a baby step toward improved treatment: Commentary on "NEOnatal Central-venous Line Observational study on Thrombosis (NEOCLOT): evaluation of a national guideline on management of neonatal catheter-related venous thrombosis"., Shannon L. Carpenter (Article)

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Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study., Craig Erker, Martin Mynarek, Simon Bailey, Claire M. Mazewski, Lorena Baroni, Maura Massimino, Juliette Hukin, Dolly Aguilera, Andrea M. Cappellano, Vijay Ramaswamy, Alvaro Lassaletta, Sébastien Perreault, Cassie N. Kline, Revathi Rajagopal, George Michaiel, Michal Zapotocky, Vicente Santa-Maria Lopez, Andres Morales La Madrid, Chantel Cacciotti, Eric S. Sandler, Lindsey M. Hoffman, Darren Klawinski, Sara Khan, Ralph Salloum, Anna L. Hoppmann, Valérie Larouche, Kathleen Dorris, Helen Toledano, Stephen W. Gilheeney, Mohamed S. Abdelbaki, Beverly Wilson, Derek S. Tsang, Jeffrey Knipstein, Michal Yalon Oren, Shafqat Shah, Jeffrey C. Murray, Kevin Ginn, Zhihong J. Wang, Gudrun Fleischhack, Denise Obrecht, Svenja Tonn, Virginia L. Harrod, Kara Matheson, Bruce Crooks, Douglas R. Strother, Kenneth J. Cohen, Jordan R. Hansford, Sabine Mueller, Ashley Margol, Amar Gajjar, Girish Dhall, Jonathan L. Finlay, Paul A. Northcott, Stefan Rutkowski, Steven C. Clifford, Giles Robinson, Eric Bouffet, and Lucie Lafay-Cousin (Article)

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Standardization of Fertility Preservation Discussion Among Pediatric Oncology and Bone Marrow Transplant Patients: A Single Institution Experience., Chandni Dargan, Sarah Mc Dermott, Shelby Chesbro, Amanda Trout, Nancy Terwilliger, Tennille Hilyard, Ashley Flynn, and Joy M. Fulbright (Article)

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Protocol and biomarker strategy for a multi-site randomized controlled trial examining biological mechanisms and dosing of active music engagement in children with acute lymphoblastic leukemia and lymphoma and parents., Sheri L. Robb, Kristen A. Russ, Steven J. Holochwost, Kristin Stegenga, Susan M. Perkins, Seethal A. Jacob, Amanda K. Henley, and Jessica A. MacLean (Article)

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Three-Year Update of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia in the ELIANA Trial., Theodore W. Laetsch, Shannon L. Maude, Susana Rives, Hidefumi Hiramatsu, Henrique Bittencourt, Peter Bader, André Baruchel, Michael Boyer, Barbara De Moerloose, Muna Qayed, Jochen Buechner, Michael A. Pulsipher, Douglas Myers, Heather E. Stefanski, Paul L. Martin, Eneida Nemecek, Christina Peters, Gregory Yanik, Seong Lin Khaw, Kara L. Davis, Joerg Krueger, Adriana Balduzzi, Nicolas Boissel, Ranjan Tiwari, Darragh O'Donovan, and Stephan A. Grupp (Article)

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Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: facilitating research through infrastructure, workforce, resources and funding., Margaret V. Ragni, Guy Young, Glaivy Batsuli, Emily Bisson, Shannon L. Carpenter, Stacy E. Croteau, Adam Cuker, Randall G. Curtis, Michael Denne, Bruce Ewenstein, Amber Federizo, Neil Frick, Kerry Funkhouser, Lindsey A. George, W Keith Hoots, Shawn M. Jobe, Emily Krava, Christopher James Langmead, Roger J. Lewis, José López, Lynn Malec, Ziva Mann, Moses E. Miles, Emma Neely, Ellis J. Neufeld, Glenn F. Pierce, Steven W. Pipe, Lisa R. Pitler, Leslie Raffini, Kathaleen M. Schnur, and Jordan A. Shavit (Article)

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Depression and anxiety in persons with Von Willebrand disease., Jonathan C. Roberts, Roshni Kulkarni, Peter A. Kouides, Robert F. Sidonio, Shannon L. Carpenter, Barbara A. Konkle, Joanne Wu, Megan M. Ullman, Randall Curtis, Judith R. Baker, Nicole Crook, and Michael B. Nichol (Article)

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Prevalence of Iron Deficiency in Patients with Inherited Bleeding Disorders, Thomas Cochran, Brian Lee, and Shannon Carpenter (Poster)

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Higher doses of tisagenlecleucel are associated with improved outcomes: a report from the pediatric real-world CAR consortium., Heather E. Stefanski, Anne Eaton, Christina Baggott, Jenna Rossoff, Michael R. Verneris, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Julie-An Talano, Amy Moskop, Steven P. Margossian, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, M Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, and Liora M. Schultz (Article)

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Data standards in pediatric oncology: Past, present, and future., Kirk D. Wyatt, David H. Noyd, Nicole Wood, Charles A. Phillips, Tamara P. Miller, Elyssa M. Rubin, Lena E. Winestone, Angela J. Waanders, John P. Perentesis, and Richard Aplenc (Article)

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Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia: secondary analyses of eight Children's Oncology Group cohort trials., Sumit Gupta, Yunfeng Dai, Zhiguo Chen, Lena E. Winestone, David T. Teachey, Kira Bona, Richard Aplenc, Karen R. Rabin, Patrick Zweidler-McKay, Andrew J. Carroll, Nyla A. Heerema, Julie Gastier-Foster, Michael J. Borowitz, Brent L. Wood, Kelly W. Maloney, Leonard A. Mattano, Eric C. Larsen, Anne L. Angiolillo, Michael J. Burke, Wanda L. Salzer, Stuart S. Winter, Patrick A. Brown, Erin M. Guest, Kimberley P. Dunsmore, John A. Kairalla, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, and Meenakshi Devidas (Article)

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Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia., Liora M. Schultz, Anne Eaton, Christina Baggott, Jenna Rossoff, Snehit Prabhu, Amy K. Keating, Christa Krupski, Holly Pacenta, Christine L. Philips, Julie-An Talano, Amy Moskop, Susanne H C Baumeister, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, Michael Kunicki, Sharon Mavroukakis, Emily Egeler, Yimei Li, Crystal L. Mackall, Kevin J. Curran, Michael R. Verneris, Theodore W. Laetsch, and Heather Stefanski (Article)

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Drugs Targeting p53 Mutations with FDA Approval and in Clinical Trials., Shigeto Nishikawa and Tomoo Iwakuma (Article)

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Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma., Dana Messinger, Micah K. Harris, Jessica R. Cummings, Chase Thomas, Tao Yang, Stefan R. Sweha, Rinette Woo, Robert Siddaway, Martin Burkert, Stefanie Stallard, Tingting Qin, Brendan Mullan, Ruby Siada, Ramya Ravindran, Michael Niculcea, Abigail R. Dowling, Joshua Bradin, Kevin Ginn, Melissa Gener, Kathleen Dorris, Nicholas A. Vitanza, Susanne V. Schmidt, Jasper Spitzer, Jiang Li, Mariella G. Filbin, Xuhong Cao, Maria G. Castro, Pedro R. Lowenstein, Rajen Mody, Arul Chinnaiyan, Pierre-Yves Desprez, Sean McAllister, Matthew D. Dun, Cynthia Hawkins, Sebastian M. Waszak, Sriram Venneti, Carl Koschmann, and Viveka Nand Yadav (Article)

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Immune System Influence on Hematopoietic Stem Cells and Leukemia Development., John M. Perry (Article)

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PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia., Xi Xu, Wenwen Zhang, Li Xuan, Yanhui Yu, Wen Zheng, Fang Tao, Jacqelyn Nemechek, Chong He, Weiwei Ma, Xue Han, Siyu Xie, Minyi Zhao, Jian Wang, Yuhua Qu, Qifa Liu, John M. Perry, Linjia Jiang, and Meng Zhao (Article)

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Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy., Laurence C. Cheung, Carlos Aya-Bonilla, Mark N. Cruickshank, Sung K. Chiu, Vincent Kuek, Denise Anderson, Grace-Alyssa Chua, Sajla Singh, Joyce Oommen, Emanuela Ferrari, Anastasia M. Hughes, Jette Ford, Elena Kunold, Maria C. Hesselman, Frederik Post, Kelly E. Faulk, Erin H. Breese, Erin M. Guest, Patrick A. Brown, Mignon L. Loh, Richard B. Lock, Ursula R. Kees, Rozbeh Jafari, Sébastien Malinge, and Rishi S. Kotecha (Article)

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Sensitivity and Specificity of Whole-body MRI for the Detection of Pediatric Malignancy., Thomas Cochran, Sachit Patel, Travis Kruse, Elizabeth Lyden, Susan Comer, and James Ford (Article)

Works from 2022

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An optimized chromatin immunoprecipitation protocol using Staph-seq for analyzing genome-wide protein-DNA interactions., Fang Tao, Egidy Rhonda, Xi He, John M. Perry, and Linheng Li (Article)

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Risk factors for hospital acquired venous thromboembolism in congenital heart disease patients: A report from the children's hospital acquired thrombosis (CHAT) consortium., Michael Silvey, Anh Thy H. Nguyen, Ernest K. Amankwah, Emily McElwaine, Brian Branchford, Amy Stillings, Emily Krava, Guy Young, Neil Goldenberg, and Julie Jaffray (Article)

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Case Report: Autoimmune anemia and thrombocytopenia following hematopoietic stem cell transplant, Thomas Cochran, Gabor Oroszi, Nancy Terwilliger, Gabe Metzler, and Lejla Music Aplenc (Poster)

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Improving infectious adverse event reporting for children and adolescents enrolled in clinical trials for acute lymphoblastic leukemia: A report from the Children's Oncology Group., Caitlin W. Elgarten, Joel Thompson, Anne Angiolillo, Zhiguo Chen, Susan Conway, Meenakshi Devidas, Sumit Gupta, John A. Kairalla, Jennifer L. McNeer, Maureen M. O'Brien, Karen R. Rabin, Rachel E. Rau, Susan R. Rheingold, Cindy Wang, Charlotte Wood, Elizabeth A. Raetz, Mignon L. Loh, Sarah Alexander, and Tamara P. Miller (Article)

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Intravenous iron therapy in the pediatric sleep clinic: a single institution experience., David G. Ingram MD, Baha Al-Shawwa MD, Lourdes M. DelRosso, and Mukta Sharma (Article)

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DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen., Shigeto Nishikawa, Atsushi Kaida, Alejandro Parrales, Atul Ranjan, Mohamed A.A. Alalem, Hongyi Ren, Frank J. Schoenen, David K. Johnson, and Tomoo Iwakuma (Article)

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MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation., Jennifer Crow, Glenson Samuel, Emily G. Farrow, Margaret Gibson, Jeffrey J. Johnston, Erin M. Guest, Neil Miller, Dong Pei, Devin Koestler, Harsh Pathak, Xiaobo Liang, Cooper Mangels, and Andrew K. Godwin (Article)

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Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness., Changzheng Li, Binghuo Wu, Yishan Li, Yaxi Liu, Jin Wang, Jiayi Xie, Xi Xu, Xiaobin Tian, Zhitao Ye, Jingjing Guan, Jie Chen, Siyu Xie, Baolin Zhang, Boyong Cai, Qianhao Wang, Haopeng Yu, Tian Lan, Cheuk Him Man, Xunlei Kang, Pengxu Qian, John M. Perry, Aibin He, Linjia Jiang, and Meng Zhao (Article)

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Clinical relevance of proteomic profiling in de novo pediatric acute myeloid leukemia: a Children's Oncology Group study, Fieke W. Hoff, Anneke D. Van Dijk, Yihua Qiu, Chenyue W. Hu, Rhonda E. Ries, Andrew Ligeralde, Gaye N. Jenkins, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Amina A. Qutub, Eveline S J M De Bont, Terzah M. Horton, and Steven M. Kornblau (Article)

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Evaluating for Suspected Child Abuse: Conditions That Predispose to Bleeding., Shannon L. Carpenter; Thomas C. Abshire; Emily Killough; James Anderst; and AAP SECTION ON HEMATOLOGY/ONCOLOGY, THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, and the AAP COUNCIL ON CHILD ABUSE AND NEGLECT (Article)

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Evaluation for Bleeding Disorders in Suspected Child Abuse., James Anderst; Shannon L. Carpenter; Thomas C. Abshire; Emily Killough; AAP SECTION ON HEMATOLOGY/ONCOLOGY, THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY, THE AAP COUNCIL ON CHILD ABUSE AND NEGLECT; Eneida A. Mendonca; Stephen M. Downs; Section on Hematology/Oncology executive committee, 2020–2021; Cynthia Wetmore; Carl Allen; David Dickens; James Harper; Zora R. Rogers; Juhi Jain; Anne Warwick; Amber Yates; Jeffrey Hord; Jeffrey Lipton; Hope Wilson; Suzanne Kirkwood; Council on Child Abuse and Neglect, 2020–2021; Suzanne B. Haney; Andrea Gottsegen Asnes; Amy R. Gavril; Rebecca Greenlee Girardet; Nancy Heavilin; Amanda Bird Hoffert Gilmartin; Antoinette Laskey; Stephen A. Messner; Bethany Anne Mohr; Shalon Marie Nienow; Norell Rosado; Council on Child Abuse and Neglect executive committee members; Sheila M. Idzerda; Lori A. Legano; Anish Raj; Andrew P. Sirotnak; Heather C. Forkey; Council on Foster Care, Adoption and Kinship Care; Brooks Keeshin; American Academy of Child and Adolescent Psychiatry; Jennifer Matjasko; Centers for Disease Control and Prevention; Heather Edward; Müge Chavdar; American Society of Pediatric Hematology/Oncology Board of Trustees, 2020–2021; Jorge Di Paola; Patrick Leavey; Doug Graham; Caroline Hastings; Nobuko Hijiya; Jeffrey Hord; Dana Matthews; Betty Pace; Maria C Velez; Dan Wechsler; Amy Billett; Linda Stork; and Ryan Hooker (Article)

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Hemostatic and Thrombotic Considerations in the Diagnosis and Management of Childhood Arterial Ischemic Stroke: A Narrative Review., Riten Kumar, Lisa R. Sun, Vilmarie Rodriguez, Amanda Sankar, Mukta Sharma, Avner Meoded, Leonardo R. Brandão, and Neil A. Goldenberg (Article)

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Novel Oncogenic PDGFRB Variant in Severe Infantile Myofibromatosis With Response to Imatinib Using Therapeutic Drug Monitoring, Abbey Elsbernd, Boutaina Boulouadnine, Atif Ahmed, Midhat S. Farooqi, Tracy L. Sandritter, Valentina Shakhnovich, Darius Blanding, Jean-Baptiste Demoulin, and Joel Thompson (Article)

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Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors., Laura van Iersel, Renee L. Mulder, Christian Denzer, Laurie E. Cohen, Helen A. Spoudeas, Lillian R. Meacham, Elaine Sugden, Antoinette Y N Schouten-van Meeteren, Eelco W. Hoving, Roger J. Packer, Gregory T. Armstrong, Sogol Mostoufi-Moab, Aline M. Stades, Dannis van Vuurden, Geert O. Janssens, Cécile Thomas-Teinturier, Robert D. Murray, Natascia Di Iorgi, Sebastian J C M M Neggers, Joel Thompson, Andrew A. Toogood, Helena Gleeson, Cecilia Follin, Edit Bardi, Lilibeth Torno, Briana Patterson, Vera Morsellino, Grit Sommer, Sarah C. Clement, Deokumar Srivastava, Cecilie E. Kiserud, Alberto Fernandez, Katrin Scheinemann, Sripriya Raman, Kevin C J Yuen, W Hamish Wallace, Louis S. Constine, Roderick Skinner, Melissa M. Hudson, Leontien C M Kremer, Wassim Chemaitilly, and Hanneke M. van Santen (Article)

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Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia., Benjamin J. Huang, Jenny L. Smith, Jason E. Farrar, Yi-Cheng Wang, Masayuki Umeda, Rhonda E. Ries, Amanda R. Leonti, Erin Crowgey, Scott N. Furlan, Katherine Tarlock, Marcos Armendariz, Yanling Liu, Timothy I. Shaw, Lisa Wei, Robert B. Gerbing, Todd M. Cooper, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Jeffrey Rubnitz, Jing Ma, Jeffery M. Klco, Xiaotu Ma, Todd A. Alonzo, Timothy Triche, and Soheil Meshinchi (Article)

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Hematopoietic Cell Transplantation in the Treatment of Pediatric Acute Myelogenous Leukemia and Myelodysplastic Syndromes: Guidelines from the American Society of Transplantation and Cellular Therapy., Katherine Tarlock, Maria Luisa Sulis, Joseph H. Chewning, Jessica A. Pollard, Todd Cooper, Alan S. Gamis, Shalini Shenoy, Matthew Kutny, John Horan, Soheil Meshinchi, Jaap-Jan Boelens, Marie Bleakley, Paul A. Carpenter, and E Anders Kolb (Article)

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Leukapheresis guidance and best practices for optimal chimeric antigen receptor T-cell manufacturing., Muna Qayed, Joseph P. McGuirk, Douglas Myers, Vinod Parameswaran, Edmund K. Waller, Peter Holman, Margarida Rodrigues, Lee F. Clough, and Jennifer Willert (Article)

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Practical considerations and consensus opinion for children's hospital-based inpatient hemostasis and thrombosis (HAT) consultative services: Communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis., Gary M. Woods, Leslie Raffini, Leonardo R. Brandão, Julie Jaffray, Brian R. Branchford, Christopher J. Ng, Sarah E. Sartain, Jennifer Pak, Christoph Male, Ayesha Zia, Mattia Rizzi, Nongnuch Sirachainan, Edward Vincent S. Faustino, Shannon L. Carpenter, and Neil A. Goldenberg (Article)

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Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin., Mohamed A.A. Alalem, Mrinalini Bhosale, Atul Ranjan, Satomi Yamamoto, Atsushi Kaida, Shigeto Nishikawa, Alejandro Parrales, Sana Farooki, Shrikant Anant, Subhash Padhye, and Tomoo Iwakuma (Article)

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A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials., Mohammed O. Gbadamosi, Vivek M. Shastri, Abdelrahman H. Elsayed, Rhonda Ries, Oluwaseyi Olabige, Nam H K Nguyen, Angelica De Jesus, Yi-Cheng Wang, Alice Dang, Betsy A. Hirsch, Todd A. Alonzo, Alan S. Gamis, Soheil Meshinchi, and Jatinder K. Lamba (Article)

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Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine., Kallen Schwark, Dana Messinger, Jessica R. Cummings, Joshua Bradin, Abed Kawakibi, Clarissa M. Babila, Samantha Lyons, Sunjong Ji, Rodrigo T. Cartaxo, Seongbae Kong, Evan Cantor, Carl Koschmann, and Viveka Nand Yadav (Article)

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Safety and efficacy of voxelotor in pediatric patients with sickle cell disease aged 4 to 11 years., Jeremie H. Estepp, Ram Kalpatthi, Gerald Woods, Sara Trompeter, Robert I. Liem, Kacie Sims, Adlette Inati, Baba P D Inusa, Andrew Campbell, Connie Piccone, Miguel R. Abboud, Kim Smith-Whitley, Sandra Dixon, Margaret Tonda, Carla Washington, Noelle M. Griffin, and Clark Brown (Article)

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Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single-institutional experience., Sarah E. Mc Dermott, Chandni Dargan, Elizabeth Gonzalez, Lejla Music Aplenc, Terrie Flatt, and Nazia Iqbal (Article)

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Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia., Amy Moskop, Lauren Pommert, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Steve P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Erin M. Guest, Erin H. Breese, and Liora M. Schultz (Article)

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A phase IV, multicentre, open-label study of emicizumab prophylaxis in people with haemophilia A with or without FVIII inhibitors undergoing minor surgical procedures., Miguel Escobar, Amy Dunn, Doris Quon, Ben Trzaskoma, Lucy Lee, Richard H. Ko, and Shannon L. Carpenter (Article)

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Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma., David T. Teachey, Meenakshi Devidas, Brent L. Wood, Zhiguo Chen, Robert J. Hayashi, Michelle L. Hermiston, Robert D. Annett, J Hunter Archer, Barbara L. Asselin, Keith August, Steve Y. Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok I. Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I. Patel, Eric S. Schafer, Tal Schechter, Neelam Singh, Amii C. Steele, Maria Luisa Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweidler-McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, and Elizabeth A. Raetz (Article)

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Informing Parents as Caregivers With a Symptom Assessment App Developed for Children With Cancer., Katherine M. Bernier Carney, Kristin Stegenga, and Lauri A. Linder (Article)

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Randomized Clinical Trial of a Self-care and Communication Intervention for Parents of Adolescent/Young Adults Undergoing High-Risk Cancer Treatment: A Report From the Children's Oncology Group., Joan E. Haase, Kristin Stegenga, Sheri L. Robb, Mary C. Hooke, Debra S. Burns, Patrick O. Monahan, Timothy E. Stump, Amanda K. Henley, Paul R. Haut, Brooke Cherven, Lona Roll, Anne-Marie Langevin, Rita H. Pickler, Karen Albritton, DeAnna Hawkins, Erin Osterkamp, Pauline Mitby, Jackie Smith, Virginia R. Diaz, Erica Garcia-Frausto, and Margo Moore (Article)