Works from 2020
Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7-18 Years., Haeyoung Zhang, Abdul Basit, Chris Wolford, Kuan-Fu Chen, Andrea Gaedigk, Yvonne S Lin, J Steven Leeder, and Bhagwat Prasad (Article)
Effects of ablation and activation of Nrf2 on bile acid homeostasis in male mice., Youcai Zhang, Andrew J. Lickteig, Jing Liu, Iván L Csanaky, and Curtis D. Klaassen (Article)
Works from 2019
Facilitating Informed Permission/Assent/Consent in Pediatric Clinical Trials., Susan M. Abdel-Rahman (Article)
Age- and Genotype-Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate-Glucuronosyltransferases in Human Liver., Deepak Kumar Bhatt, Aanchal Mehrotra, Andrea Gaedigk, Revathi Chapa, Abdul Basit, Haeyoung Zhang, Prachi Choudhari, Mikael Boberg, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, J Steven Leeder, and Bhagwat Prasad (Article)
Cardiovascular benefits of tyrosol and its endogenous conversion into hydroxytyrosol in humans. A randomized, controlled trial., Anna Boronat, Julian Mateus, Natalia Soldevila-Domenech, Mercè Guerra, Jose Rodríguez-Morató, Carlota Varon, Daniel Muñoz, Francina Barbosa, Juan Carlos Morales, Andrea Gaedigk, Klaus Langohr, Maria-Isabel Covas, Clara Pérez-Mañá, Montserrat Fitó, Rachel F. Tyndale, and Rafael de la Torre (Article)
Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans., Anna Boronat, Julian Mateus, Natalia Soldevila-Domenech, Mercè Guerra, Jose Rodríguez-Morató, Carlota Varon, Daniel Muñoz, Francina Barbosa, Juan Carlos Morales, Andrea Gaedigk, Klaus Langohr, Maria-Isabel Covas, Clara Pérez-Mañá, Montserrat Fitó, Rachel F. Tyndale, and Rafael de la Torre (Article)
Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles., Mariana R. Botton, Xingwu Lu, Geping Zhao, Elena Repnikova, Yoshinori Seki, Andrea Gaedigk, Eric E. Schadt, Lisa Edelmann, and Stuart A. Scott (Article)
Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy., Jacob T. Brown, Jeffrey R. Bishop, Katrin Sangkuhl, Erika L. Nurmi, Daniel J. Mueller, Jean C. Dinh, Andrea Gaedigk, Teri E. Klein, Kelly E. Caudle, James T. McCracken, Jose de Leon, and J Steven Leeder (Article)
Improving Recognition and Reporting of Adverse Drug Reactions in the NICU: A Quality Improvement Project., Betsy Cammack, Alexandra Oschman, and Tamorah R. Lewis MD PhD (Article)
Opioid Prescribing Practices in Pediatric Acute Care Settings., Michelle DePhillips, Jennifer Watts, Jennifer Lowry, and M Denise Dowd (Article)
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy., Zeruesenay Desta, Roseann S. Gammal, Li Gong, Michelle Whirl-Carrillo, Aditya H. Gaur, Chonlaphat Sukasem, Jennifer Hockings, Alan Myers, Marelize Swart, Rachel F. Tyndale, Collen Masimirembwa, Otito F. Iwuchukwu, Sanika Chirwa, Jeffrey Lennox, Andrea Gaedigk, Teri E. Klein, and David W. Haas (Article)
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit., Jamesia Donato, Karishma Rao, and Tamorah R. Lewis MD PhD (Article)
Developmental Expression of the Cytosolic Sulfotransferases in Human Liver., Sarah Dubaisi, Joseph A. Caruso, R Gaedigk, Carrie A. Vyhlidal, Philip C. Smith, Ronald N. Hines, Thomas A. Kocarek, and Melissa Runge-Morris (Article)
Pharmacogenetics: Chasing Perfection., Andrea Gaedigk (Editorial)
The Evolution of PharmVar., Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P. Twist, Teri E. Klein, Neil A. Miller, and PharmVar Steering Committee (Article)
Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project., Andrea Gaedigk, Amy Turner, Robin E. Everts, Stuart A. Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A. McMillin, Roberta Melis, Erin C. Boone, Victoria M. Pratt, and Lisa V. Kalman (Article)
The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children., Roseann S. Gammal, Kelly E. Caudle, Charles T. Quinn, Winfred C. Wang, Andrea Gaedigk, Cynthia A. Prows, Cyrine E. Haidar, Annette K. Taylor, Teri E. Klein, Katrin Sangkuhl, Jane S. Hankins, and Kristine R. Crews (Article)
Ethylene Glycol and Other Glycols: Analytical and Interpretation Issues, Uttam Garg, Jennifer Lowry, and D Adam Algren (Book Chapter)
Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement., Jennifer Goldman, Wen-Hung Chung, Brian R. Lee, Chun-Bing Chen, Chun-Wei Lu, Wolfram Hoetzenecker, Robert Micheletti, Sally Usdin Yasuda, David J. Margolis, Neil H. Shear, Jeffery P. Struewing, and Munir Pirmohamed (Article)
Population pharmacokinetics of sildenafil in extremely premature infants., Daniel Gonzalez, Matthew M. Laughon, P Brian Smith, Shufan Ge, Namasivayam Ambalavanan, Andrew Atz, Gregory M. Sokol, Chi D. Hornik, Dan Stewart, Gratias Mundakel, Brenda B. Poindexter, R Gaedigk, Mary Mills, Michael Cohen-Wolkowiez, Karen Martz, Christoph P. Hornik, and Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee (Article)
Acetaminophen Protein Adducts in Hospitalized Children Receiving Multiple Doses of Acetaminophen., Sibo Jiang, Valvanera Vozmediano, Susan M. Abdel-Rahman, Stephan Schmidt, and Laura P. James (Article)
Drug Dose Selection in Pediatric Obesity: Available Information for the Most Commonly Prescribed Drugs to Children, Kathyrn Kyler, Jonathan B. Wagner, Chelsea Hosey-Cojocari, Kevin Watt, and Valentina Shakhnovich (Article)
Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism., Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J Steven Leeder, Michael B. Bolger, Saranjit Singh, and Bhagwat Prasad (Article)
Who Believes They Are "Just Average": Informing the Treatment of Individual Patients Using Population Data., J Steven Leeder (Article)
Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model., Seung-Been Lee, Marsha M. Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L. Woodahl, Andrea Gaedigk, Kenneth E. Thummel, and Deborah A. Nickerson (Article)
Optimized Renal Transporter Quantification by Using Aquaporin 1 and Aquaporin 2 as Anatomical Markers: Application in Characterizing the Ontogeny of Renal Transporters and Its Correlation with Hepatic Transporters in Paired Human Samples., Cindy Yanfei Li, Chelsea Hosey-Cojocari, Abdul Basit, Jashvant D Unadkat, J Steven Leeder, and Bhagwat Prasad (Article)
Effects of Absence of Constitutive Androstane Receptor (CAR) on Bile Acid Homeostasis in Male and Female Mice., Andrew J. Lickteig, Youcai Zhang, Curtis D. Klaassen, and Iván L. Csanaky (Article)
Examining the role of precision medicine with oral baclofen in pediatric patients with cerebral palsy., Matthew J. McLaughlin, Susan M. Abdel-Rahman, and J Steven Leeder (Article)
Considerations for Implementing Precision Therapeutics for Children., Matthew J. McLaughlin, Jonathan B. Wagner, Valentina Shakhnovich, Bruce Carleton, and J Steven Leeder (Article)
Assessing effectiveness of a novel mid-upper arm circumference Z-score tape in a community setting in Guatemala., Mikaela A. Miller, Kristen Mallory, Manolo Escobedo, Ana Cecilia Tarot, and Susan M. Abdel-Rahman (Article)
Description of an Innovative Pediatric Individualized Therapeutics Clinic: Working toward Precision Drug Therapy., Tracy L. Sandritter, Jean C. Dinh, Jennifer A. Wagner, and Jennifer Lowry (Article)
An electronic medical records-based approach to identify idiosyncratic drug-induced liver injury in children., Tracy L. Sandritter, Jennifer Goldman, Clayton J Habiger, James F. Daniel, Jennifer Lowry, and Ryan T. Fischer (Article)
Visible-Light-Activated High-Density Materials for Controlled in Vivo Insulin Release., Bhagyesh R. Sarode, Karen Kover, and Simon H. Friedman (Article)
Lean body weight dosing avoids excessive systemic exposure to proton pump inhibitors for children with obesity, Valentina Shakhnovich, Susan M. Abdel-Rahman, Craig A. Friesen, J. Weigel, Robin E. Pearce, Andrea Gaedigk, J Steven Leeder, and G. L. Kearns (Article)
Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model., Rakesh K. Singh, Leon van Haandel, Paul Kiptoo, Mara L. Becker, Teruna J. Siahaan, and Ryan S. Funk (Article)
Naltrexone Reduces Binge Eating and Purging in Adolescents in an Eating Disorder Program., Stephani L. Stancil, William P. Adelman, Amanda Dietz, and Susan M. Abdel-Rahman (Article)
Evaluating metronidazole as a novel, safe CYP2A6 phenotyping probe in healthy adults., Stephani L. Stancil, Robin E. Pearce, Rachel F. Tyndale, Gregory L. Kearns, Carrie A. Vyhlidal, J Steven Leeder, and Susan M. Abdel-Rahman (Article)
Children Are Not Small Adults: Specific Findings in Statin Exposure and Response in a Growing Population., Jonathan B. Wagner (Article)
Genomics and Precision Medicine to Direct Statin Use in the Young., Jonathan B. Wagner (Article)
Impact of Genetic Variation on Pravastatin Systemic Exposure in Pediatric Hypercholesterolemia., Jonathan B. Wagner, Susan M. Abdel-Rahman, R Gaedigk, Andrea Gaedigk, Geetha Raghuveer, Vincent S. Staggs, Ralph Kauffman, Leon Van Haandel, and J Steven Leeder (Article)
Pharmacogene Variation Consortium Gene Introduction: NUDT15., Jun J. Yang, Michelle Whirl-Carrillo, Stuart A. Scott, Amy J. Turner, Matthias Schwab, Yoichi Tanaka, Guilherme Suarez-Kurtz, Elke Schaeffeler, Teri E. Klein, Neil A. Miller, and Andrea Gaedigk (Article)
Works from 2018
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex., Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-Been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J Steven Leeder, and Bhagwat Prasad (Article)
Variability of surgical prophylaxis in penicillin-allergic children., David F. Butler, Brian R. Lee, Sarah Suppes, Tracy Sandritter, Jason G. Newland, Lory Harte, and Jennifer Goldman (Article)
Hydroxycarbamide in children with sickle cell anaemia after first-dose vs. chronic therapy: pharmacokinetics and predictive models for drug exposure., Jeremie H. Estepp, Paweł Wiczling, Joseph Moen, Guolian Kang, Joana Marie Mack, Robert Liem, Julie A. Panepinto, Uttam Garg, Gregory Kearns, and Kathleen A. Neville (Article)
Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics., Andrea Gaedigk, Jean C. Dinh, Hyunyoung Jeong, Bhagwat Prasad, and J Steven Leeder (Article)
Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions., Jennifer Goldman and Leon van Haandel (Article)
PharmGKB summary: clobazam pathway, pharmacokinetics., Rachel Huddart, J Steven Leeder, Russ B. Altman, and Teri E. Klein (Article)
Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing., Tamorah R. Lewis, Leon Van Haandel, Allison Scott, and J Steven Leeder (Response or Comment)
Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis., Teri A. Manolio, Carolyn M. Hutter, Mark Avigan, Ricardo Cibotti, Robert L. Davis, Joshua C. Denny, Lois La Grenade, Lisa M. Wheatley, Mary N. Carrington, Wasun Chantratita, Wen-Hung Chung, Andrea D. Dalton, Shuen-Iu Hung, Ming Ta Michael Lee, J Steven Leeder, Juan J L Lertora, Surakameth Mahasirimongkol, Howard L. McLeod, Maja Mockenhaupt, Michael Pacanowski, Elizabeth J. Phillips, Simone Pinheiro, Munir Pirmohamed, Cynthia Sung, Wimon Suwankesawong, Lauren Trepanier, Santa J. Tumminia, David Veenstra, Rika Yuliwulandari, and Neil H. Shear (Article)
Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy., Matthew J. McLaughlin, Yang He, Janice Brunstrom-Hernandez, Liu Lin Thio, Bruce C. Carleton, Colin J D Ross, Andrea Gaedigk, Andrew Lewandowski, Hongying Dai, William J. Jusko, and J Steven Leeder (Article)
Response to 'Aprepitant and fosaprepitant decrease the effectiveness of hormonal contraceptives'., Priya Patel, J Steven Leeder, Micheline Piquette-Miller, and L Lee Dupuis (Response or Comment)
The NSIGHT1-randomized controlled trial: rapid whole-genome sequencing for accelerated etiologic diagnosis in critically ill infants., Joshua E. Petrikin, Julie A. Cakici, Michelle M. Clark, Laurel K. Willig, Nathaly M. Sweeney, Emily G. Farrow, Carol J. Saunders, Isabelle Thiffault, Neil A. Miller, Lee Zellmer, Suzanne M. Herd, Anne Holmes, Serge Batalov, Narayanan Veeraraghavan, Laurie D. Smith, David P. Dimmock, J Steven Leeder, and Stephen F. Kingsmore (Article)
It's Time to Reverse our Thinking: The Reverse Translation Research Paradigm, Valentina Shakhnovich (Editorial)
A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents, Valentina Shakhnovich, P. Brian Smith, Jeffrey T. Guptill, Laura P. James, David N. Collier, Huali Wu, Chad E. Livingston, Jian Zhao, Gregory L. Kearns, and Michael Cohen-Wolkowiez (Article)
Reply, Valentina Shakhnovich, P. Brian Smith, Huali Wu, Michael Cohen-Wolkowiez, and Gregory L. Kearns (Letter to the Editor)
Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP., Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J Steven Leeder, Mara L. Becker, and Ryan S. Funk (Article)
Development of a UPLC-MS/MS method for quantitation of metronidazole and 2-hydroxy metronidazole in human plasma and its application to a pharmacokinetic study., Stephani L. Stancil, Leon van Haandel, Susan M. Abdel-Rahman, and Robin E. Pearce (Article)
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants., Bianca D. van Groen, Evita van de Steeg, Miriam G. Mooij, Marola M H van Lipzig, Barbara A E de Koning, Robert M. Verdijk, Heleen M. Wortelboer, R Gaedigk, Chengpeng Bi, J Steven Leeder, Ron H N van Schaik, Joost van Rosmalen, Dick Tibboel, Wouter H. Vaes, and Saskia N. de Wildt (Article)
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects., Simona Volpi, Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Howard J. Jacob, Melpomeni Kasapi, Howard L. McLeod, Dan M. Roden, Marc S. Williams, Eric D. Green, Laura Lyman Rodriguez, Samuel Aronson, Larisa H. Cavallari, Joshua C. Denny, Lynn G. Dressler, Julie A. Johnson, Teri E. Klein, J Steven Leeder, Micheline Piquette-Miller, Minoli Perera, Laura J. Rasmussen-Torvik, Heidi L. Rehm, Marylyn D. Ritchie, Todd C. Skaar, Nikhil Wagle, Richard Weinshilboum, Kristin W. Weitzel, Robert Wildin, John Wilson, Teri A. Manolio, and Mary V. Relling (Article)
Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics., Jonathan B. Wagner, Susan M. Abdel-Rahman, Leon Van Haandel, Andrea Gaedigk, R Gaedigk, Geetha Raghuveer, Ralph Kauffman, and J Steven Leeder (Article)
Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice., Li Q. Zhang, Marianne Nsumu, Peixin Huang, Daniel P. Heruth, Sean M. Riordan, Katherine Shortt, Nini Zhang, Dmitry N. Grigoryev, Ding-You Li, Craig A. Friesen, Leon Van Haandel, J Steven Leeder, Jody Olson, and Shui Q. Ye (Article)
Works from 2017
Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants., Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J Steven Leeder, and Bhagwat Prasad (Article)
A comparison of 7-day versus 10-day course of low-dose dexamethasone for chronically ventilated preterm infants., Alain Cuna, S Govindarajan, Alexandra Oschman, H Dai, K Brophy, Michael Norberg, and William E. Truog (Article)
Prediction of CYP2D6 phenotype from genotype across world populations., Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, and J Steven Leeder (Article)
In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report., Andrea Gaedigk, Greyson P. Twist, Emily G. Farrow, Jennifer A. Lowry, Sarah E. Soden, and Neil A. Miller (Article)
Variability in Antifungal and Antiviral Use in Hospitalized Children., Jennifer L. Goldman, Rachael K. Ross, Brian R. Lee, Jason G. Newland, Adam L. Hersh, Matthew P. Kronman, and Jeffrey S. Gerber (Article)
Intravenous Versus Oral Antibiotics for the Prevention of Treatment Failure in Children With Complicated Appendicitis: Has the Abandonment of Peripherally Inserted Catheters Been Justified?, Shawn J. Rangel, Brett R. Anderson, Rajendu Srivastava, Samir S. Shah, Paul Ishimine, Mythili Srinivasan, Matthew Bryan, Wu Gong, Matt Hall, Russell Localio, Xianqun Luan, Seema Anandalwar, Ron Keren, and Pediatric Research in Inpatient Settings (PRIS) Network (Article)
The Interplay between Pharmacokinetics and Pharmacodynamics., Tracy L. Sandritter, Matthew J. McLaughlin, Michael Artman, and Jennifer Lowry (Article)
Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation., Laura A. Wang, Daniel Gonzalez, J Steven Leeder, Rachel F. Tyndale, Robin E. Pearce, Daniel K. Benjamin, Gregory L. Kearns, Michael Cohen-Wolkowiez, and Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee (Article)
Works from 2016
Design and Testing of an EHR-Integrated, Busulfan Pharmacokinetic Decision Support Tool for the Point-of-Care Clinician., Susan M. Abdel-Rahman, Matthew L. Breitkreutz, Charlie Bi, Brett J. Matzuka, Jignesh Dalal, K Leigh Casey, Uttam Garg, Sara Winkle, J Steven Leeder, JeanAnn Breedlove, and Brian Rivera (Article)
A Simple Liquid Chromatography Tandem Mass Spectrometry Method for Quantitation of Plasma Busulfan., Shuang Deng, Michael Kiscoan, C. Clinton Frazee III, Susan M. Abdel-Rahman, Jignesh Dalal, and Uttam Garg (Article)
Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort., T M. Dodgen, C De J De J Labuschagne, A van Schalkwyk, F E. Steffens, Andrea Gaedigk, A D. Cromarty, M Alessandrini, and M S. Pepper (Article)
Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology., Uttam Garg and Yan Victoria Zhang (Article)
Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes., Jennifer Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, J Steven Leeder, and Robert P. Hanzlik (Article)
Tablet/Capsule Size Variation Among the Most Commonly Prescribed Medications for Children in the USA: Retrospective Review and Firsthand Pharmacy Audit., Laura Jacobsen, Kathy Riley, Brian R. Lee, Kathleen Bradford, and Ravi Jhaveri (Article)
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting., L V. Kalman, Jag Agúndez, M Lindqvist Appell, J L. Black, G C. Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A. Coulthard, A K. Daly, Al Del Tredici, J T. den Dunnen, K Drozda, R E. Everts, D Flockhart, R R. Freimuth, Andrea Gaedigk, H Hachad, T Hartshorne, M Ingelman-Sundberg, T E. Klein, V M. Lauschke, D R. Maglott, H L. McLeod, G A. McMillin, U A. Meyer, D J. Müller, D A. Nickerson, W S. Oetting, M Pacanowski, V M. Pratt, M V. Relling, A Roberts, W S. Rubinstein, K Sangkuhl, M Schwab, S A. Scott, S C. Sim, R K. Thirumaran, L H. Toji, R F. Tyndale, Rhn van Schaik, M Whirl-Carrillo, KTJ Yeo, and U M. Zanger (Article)
Clindamycin-susceptibility rates of methicillin-resistant staphylococcus aureus varies by infection type in pediatric patients, Amanda Li, Rangaraj Selvarangan, Richard K. Ogden Jr., Brandon French, and Diana Yu (Article)
Stochastic nonlinear mixed effects: a metformin case study., Brett Matzuka, Jason Chittenden, Jonathan Monteleone, and Hien Tran (Article)
Cetirizine Quantification by High-Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)., Ada Munar, C. Clinton Frazee III, Bridgette Jones, and Uttam Garg (Article)
Yinzhihuang attenuates ANIT-induced intrahepatic cholestasis in rats through upregulation of Mrp2 and Bsep expressions., Qiao-Qun Ou, Xin-Hua Qian, Ding-You Li, You-Xiang Zhang, Xia-Nan Pei, Jin-Wen Chen, and Li Yu (Article)
Quantification of Free Phenytoin by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)., Judy Peat, C. Clinton Frazee III, and Uttam Garg (Article)
Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics., B Prasad, Andrea Gaedigk, M Vrana, R Gaedigk, J Steven Leeder, L Salphati, X Chu, G Xiao, Ceca Hop, R Evers, L Gan, and J D Unadkat (Article)
Comprehensive Urine Drug Screen by Gas Chromatography/Mass Spectrometry (GC/MS)., Bheemraj Ramoo, Melissa Funke, C. Clinton Frazee III, and Uttam Garg (Article)
CYP450 genotype and pharmacogenetic association studies: a critical appraisal., Rashmi R. Shah, Andrea Gaedigk, Adrián LLerena, Michel Eichelbaum, Julia Stingl, and Robert L. Smith (Article)
Long-term velaglucerase alfa treatment in children with Gaucher disease type 1 naïve to enzyme replacement therapy or previously treated with imiglucerase., Laurie Smith, William Rhead, Joel Charrow, Suma P. Shankar, Ashish Bavdekar, Nicola Longo, Rebecca Mardach, Paul Harmatz, Thomas Hangartner, Hak-Myung Lee, Eric Crombez, and Gregory M. Pastores (Article)
Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene,, Greyson P. Twist, Andrea Gaedigk, Neil A. Miller, Emily G. Farrow, Laurel K. Willig, Darrell L. Dinwiddie, Josh E. Petrikin, Sarah E. Soden, Suzanne Herd, Margaret Gibson, Julie A. Cakici, Amanda K. Riffel, J Steven Leeder, Deendayal Dinakarpandian, and Stephen F. Kingsmore (Article)
Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study., Leon van Haandel, Kim T. Gibson, J Steven Leeder, and Jonathan B. Wagner (Article)
Works from 2015
Comparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children., Ron Keren, Samir S. Shah, Rajendu Srivastava, Shawn Rangel, Michael Bendel-Stenzel, Nada Harik, John Hartley, Michelle Lopez, Luis Seguias, Joel Tieder, Matthew Bryan, Wu Gong, Matt Hall, Russell Localio, Xianqun Luan, Rachel deBerardinis, Allison Parker, Pediatric Research in Inpatient Settings Network, and Jeffrey D. Colvin (Article)
CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6 (*) 15 and (*) 35 Genotyping., Amanda K. Riffel, Mehdi Dehghani, Toinette Hartshorne, Kristen C. Floyd, J Steven Leeder, Kevin P. Rosenblatt, and Andrea Gaedigk (Article)
Works from 2014
General considerations for pediatric oral drug formulation, Valentina Shakhnovich and Susan M. Abdel-Rahman (Book Chapter)
Works from 2013
Pediatric pharmacokinetics., Jonathan B. Wagner and Susan M. Abdel-Rahman (Article)
