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Works from 2017

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Prediction of CYP2D6 phenotype from genotype across world populations., Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, and J Steven Leeder (Article)

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In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report., Andrea Gaedigk, Greyson P. Twist, Emily G. Farrow, Jennifer A. Lowry, Sarah E. Soden, and Neil A. Miller (Article)

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Variability in Antifungal and Antiviral Use in Hospitalized Children., Jennifer L. Goldman, Rachael K. Ross, Brian R. Lee, Jason G. Newland, Adam L. Hersh, Matthew P. Kronman, and Jeffrey S. Gerber (Article)

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Intravenous Versus Oral Antibiotics for the Prevention of Treatment Failure in Children With Complicated Appendicitis: Has the Abandonment of Peripherally Inserted Catheters Been Justified?, Shawn J. Rangel, Brett R. Anderson, Rajendu Srivastava, Samir S. Shah, Paul Ishimine, Mythili Srinivasan, Matthew Bryan, Wu Gong, Matt Hall, Russell Localio, Xianqun Luan, Seema Anandalwar, Ron Keren, and Pediatric Research in Inpatient Settings (PRIS) Network (Article)

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The Interplay between Pharmacokinetics and Pharmacodynamics., Tracy L. Sandritter, Matthew J. McLaughlin, Michael Artman, and Jennifer Lowry (Article)

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Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation., Laura A. Wang, Daniel Gonzalez, J Steven Leeder, Rachel F. Tyndale, Robin E. Pearce, Daniel K. Benjamin, Gregory L. Kearns, Michael Cohen-Wolkowiez, and Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee (Article)

Works from 2016

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Design and Testing of an EHR-Integrated, Busulfan Pharmacokinetic Decision Support Tool for the Point-of-Care Clinician., Susan M. Abdel-Rahman, Matthew L. Breitkreutz, Charlie Bi, Brett J. Matzuka, Jignesh Dalal, K Leigh Casey, Uttam Garg, Sara Winkle, J Steven Leeder, JeanAnn Breedlove, and Brian Rivera (Article)

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A Simple Liquid Chromatography Tandem Mass Spectrometry Method for Quantitation of Plasma Busulfan., Shuang Deng, Michael Kiscoan, C. Clinton Frazee III, Susan M. Abdel-Rahman, Jignesh Dalal, and Uttam Garg (Article)

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Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort., T M. Dodgen, C De J De J Labuschagne, A van Schalkwyk, F E. Steffens, Andrea Gaedigk, A D. Cromarty, M Alessandrini, and M S. Pepper (Article)

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Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology., Uttam Garg and Yan Victoria Zhang (Article)

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Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes., Jennifer Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, J Steven Leeder, and Robert P. Hanzlik (Article)

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Tablet/Capsule Size Variation Among the Most Commonly Prescribed Medications for Children in the USA: Retrospective Review and Firsthand Pharmacy Audit., Laura Jacobsen, Kathy Riley, Brian R. Lee, Kathleen Bradford, and Ravi Jhaveri (Article)

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Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting., L V. Kalman, Jag Agúndez, M Lindqvist Appell, J L. Black, G C. Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A. Coulthard, A K. Daly, Al Del Tredici, J T. den Dunnen, K Drozda, R E. Everts, D Flockhart, R R. Freimuth, Andrea Gaedigk, H Hachad, T Hartshorne, M Ingelman-Sundberg, T E. Klein, V M. Lauschke, D R. Maglott, H L. McLeod, G A. McMillin, U A. Meyer, D J. Müller, D A. Nickerson, W S. Oetting, M Pacanowski, V M. Pratt, M V. Relling, A Roberts, W S. Rubinstein, K Sangkuhl, M Schwab, S A. Scott, S C. Sim, R K. Thirumaran, L H. Toji, R F. Tyndale, Rhn van Schaik, M Whirl-Carrillo, KTJ Yeo, and U M. Zanger (Article)

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Clindamycin-susceptibility rates of methicillin-resistant staphylococcus aureus varies by infection type in pediatric patients, Amanda Li, Rangaraj Selvarangan, Richard K. Ogden Jr., Brandon French, and Diana Yu (Article)

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Stochastic nonlinear mixed effects: a metformin case study., Brett Matzuka, Jason Chittenden, Jonathan Monteleone, and Hien Tran (Article)

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Cetirizine Quantification by High-Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)., Ada Munar, C. Clinton Frazee III, Bridgette Jones, and Uttam Garg (Article)

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Yinzhihuang attenuates ANIT-induced intrahepatic cholestasis in rats through upregulation of Mrp2 and Bsep expressions., Qiao-Qun Ou, Xin-Hua Qian, Ding-You Li, You-Xiang Zhang, Xia-Nan Pei, Jin-Wen Chen, and Li Yu (Article)

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Quantification of Free Phenytoin by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)., Judy Peat, C. Clinton Frazee III, and Uttam Garg (Article)

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Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics., B Prasad, Andrea Gaedigk, M Vrana, R Gaedigk, J Steven Leeder, L Salphati, X Chu, G Xiao, Ceca Hop, R Evers, L Gan, and J D Unadkat (Article)

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Comprehensive Urine Drug Screen by Gas Chromatography/Mass Spectrometry (GC/MS)., Bheemraj Ramoo, Melissa Funke, C. Clinton Frazee III, and Uttam Garg (Article)

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CYP450 genotype and pharmacogenetic association studies: a critical appraisal., Rashmi R. Shah, Andrea Gaedigk, Adrián LLerena, Michel Eichelbaum, Julia Stingl, and Robert L. Smith (Article)

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Long-term velaglucerase alfa treatment in children with Gaucher disease type 1 naïve to enzyme replacement therapy or previously treated with imiglucerase., Laurie Smith, William Rhead, Joel Charrow, Suma P. Shankar, Ashish Bavdekar, Nicola Longo, Rebecca Mardach, Paul Harmatz, Thomas Hangartner, Hak-Myung Lee, Eric Crombez, and Gregory M. Pastores (Article)

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Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene,, Greyson P. Twist, Andrea Gaedigk, Neil A. Miller, Emily G. Farrow, Laurel K. Willig, Darrell L. Dinwiddie, Josh E. Petrikin, Sarah E. Soden, Suzanne Herd, Margaret Gibson, Julie A. Cakici, Amanda K. Riffel, J Steven Leeder, Deendayal Dinakarpandian, and Stephen F. Kingsmore (Article)

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Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study., Leon van Haandel, Kim T. Gibson, J Steven Leeder, and Jonathan B. Wagner (Article)

Works from 2015

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Comparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children., Ron Keren, Samir S. Shah, Rajendu Srivastava, Shawn Rangel, Michael Bendel-Stenzel, Nada Harik, John Hartley, Michelle Lopez, Luis Seguias, Joel Tieder, Matthew Bryan, Wu Gong, Matt Hall, Russell Localio, Xianqun Luan, Rachel deBerardinis, Allison Parker, Pediatric Research in Inpatient Settings Network, and Jeffrey D. Colvin (Article)

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CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6 (*) 15 and (*) 35 Genotyping., Amanda K. Riffel, Mehdi Dehghani, Toinette Hartshorne, Kristen C. Floyd, J Steven Leeder, Kevin P. Rosenblatt, and Andrea Gaedigk (Article)

Works from 2014

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General considerations for pediatric oral drug formulation, Valentina Shakhnovich and Susan M. Abdel-Rahman (Book Chapter)

Works from 2013

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Pediatric pharmacokinetics., Jonathan B. Wagner and Susan M. Abdel-Rahman (Article)